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comment_83107

Has anyone automated the immediate spin and the IgG crossmatch using the Ortho Vision?

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  • Mabel Adams
    Mabel Adams

    We have for IgG XM but not IS.  The latter is very fast in tube and we don't do it except during computer downtimes and some rare occasions.  We use the electronic XM for most.

  • We use Immucor ECHO Lumena and, as of right now, it does not do the IS XM. If it did, I would absolutely validate and run them on the automated platform. The reason I say that is because of the staffi

  • John C. Staley
    John C. Staley

    I'm not sure if this is still the case but the IS step was intended to confirm ABO compatibility.   

comment_83180

We have for IgG XM but not IS.  The latter is very fast in tube and we don't do it except during computer downtimes and some rare occasions.  We use the electronic XM for most.

comment_83182
11 hours ago, Mabel Adams said:

We have for IgG XM but not IS.  The latter is very fast in tube and we don't do it except during computer downtimes and some rare occasions.  We use the electronic XM for most.

We are the same here.

comment_83184

We use Immucor ECHO Lumena and, as of right now, it does not do the IS XM. If it did, I would absolutely validate and run them on the automated platform. The reason I say that is because of the staffing and competency issues we are currently experiencing and is forecasted to only get worse. I cannot keep consistent blood bank techs in the blood bank and the generalists, who are often new and weak, do not remember to do the IS portion. I am constantly having to remind them and perform the retroactively. Sure, I can write them up each time but then I would have no one to work the blood bank. Having that on automation eliminates the problem. I did the same with antigen typing, cord bloods, unit retypes, and anything else I could move to automation, simply to make it easier for the generalists. It also provides peace of mind and a level of safety, where I can go back and clearly see what was done. No more wondering whether they added plasma to the tube or not. 

Just my two cents.

comment_83193

It is my understanding that the Ortho Vision is not 'licensed" for immediate-spin compatibility testing. (Licensed may not be the correct terminology)  Please refer to Ortho published materials for immediate-spin eligibility.

comment_83213

Sorry for my ignorance, I have never used the vision. Would you need two different cards, one for IgG and one for IS? If the cards exist why could you not validate their use? As jayinsat said automation helps the generalists especially when short staffed or they are inexperienced. 

comment_83259

IS XM in Ortho gel uses the neutral card, while IAT XM requires the IgG card. We don't currently stock the neutral gel cards.  Our small hospitals are gel-only so any IS XMs needed there are done by using the neutral wells in the ABD/Reverse card that were intended for the reverse type.  They do these maybe once a year at most.

comment_83262
1 hour ago, Mabel Adams said:

IS XM in Ortho gel uses the neutral card, while IAT XM requires the IgG card. We don't currently stock the neutral gel cards.  Our small hospitals are gel-only so any IS XMs needed there are done by using the neutral wells in the ABD/Reverse card that were intended for the reverse type.  They do these maybe once a year at most.

It sounds like IS XM can easily be part of a hospitals automated system using the neutral card. Do/can the results move over to the LIS when validated?

comment_83265

If IS XM can be a test on the Vision, I would think it could go through the interface like the AHG XM does.  Might depend on your BBIS.

comment_83268
On 4/4/2022 at 5:25 PM, Mabel Adams said:

We have for IgG XM but not IS.  The latter is very fast in tube and we don't do it except during computer downtimes and some rare occasions.  We use the electronic XM for most.

Same here.  It wasn't that long ago when Electronic XM's weren't a thing. I find it so amazing how far technology has "improved" blood banking in a relatively short time.  

  • 2 weeks later...
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comment_83324
On 4/8/2022 at 6:29 AM, Ensis01 said:

Sorry for my ignorance, I have never used the vision. Would you need two different cards, one for IgG and one for IS? If the cards exist why could you not validate their use? As jayinsat said automation helps the generalists especially when short staffed or they are inexperienced. 

FDA approval came through last year.

  • Author
comment_83350

Thanks, everyone. I wanted to validate it especially for 2nd/ 3rd shift staff when there is only 1 tech staffed in the blood bank. They could put on the segment, sample then do other things.

  • 1 year later...
comment_87725

Can anyone help me understand why the immediate spin XM step is required if you are performing the IgG XM on gel? I am struggling to find guidance on this.

comment_87730
19 hours ago, ryffelj said:

Can anyone help me understand why the immediate spin XM step is required if you are performing the IgG XM on gel? I am struggling to find guidance on this.

I'm not sure if this is still the case but the IS step was intended to confirm ABO compatibility.   

:coffeecup:

comment_87765

Buffer cards/ IS XM are validated for detecting ABO incompatability.  The IGG card has not been validated to detect all possibilities of ABO incomp per the IFU.  The Vision can be configured to perform ISXM and IAT XM simultaneously.  

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