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Malcolm Needs

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Malcolm Needs last won the day on March 14

Malcolm Needs had the most liked content!

About Malcolm Needs

  • Birthday 12/14/1954

Profile Information

  • Gender
    Male
  • Interests
    Rugby Union, Cricket, cooking, wine, port, reading, crosswords, lecturing, more wine and more port!
  • Biography
    Pretty boring really, but not that pretty!
  • Location
    Sourton, Devon, England
  • Occupation
    Prior to retirement, I had taken a brand-new role in the NHSBT and was involved very much more on the education and training side of red cell immunohaematology. My title was Reference Service Manager, but with Training after it (Reference Service Manager - Training). I was very excited about this change, as I have a passion for training and education.
    Reference Service Manager with the NHSBT.
    Ex-Chartered Scientist.
    Fellow of the British Blood Transfusion Society, having twice served on their National Council.
    Ex-Fellow of the Institute of Biomedical Science. Ex-member of their Special Advisory Panel for Transfusion Science and Chief Examiner for Transfusion Science for the Institute.
    Author of the chapter "Human erythrocyte antigens or blood groups" in Fundamentals of Biomedical Science, Transfusion and Transplantation Science, edited by Robin Knight, for the IBMS. 1st edition, Oxford University Press 2013 (ISBN 978-0-19-953328-2, pages 19-44.
    Was a member of the BSH Blood Transfusion Task Force (writing Guidelines).
    Member of ISBT and AABB
    I am now retired from the Blood Service, but still do the other things!
  • Real Name
    Malcolm Needs FBBTS

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Malcolm Needs's Achievements

  1. I just answered this question. My Score PASS  
  2. Welcome to this FANTASTIC site Rajendra Chaudhary. RNJOY!
  3. NOBODY has EVER performed either an Indirect Coombs Test (ICT) (or, still worse, an Indirect Coombes Test), or a Direct Coombs Test (DCT) (or, still worse, a Direct Coombes Test). There is most certainly NOT either an Indirect or Direct AHG Test. AHG is a reagent used in both the IAT and the DAT. The correct terminology for the former test is the Indirect Antiglobulin Test (IAT) and for the latter test is the Direct Antiglobulin Test (DAT). It is true that Coombs was the primary author on three papers describing the test1-3, but Mourant and Race were his co-authors on these papers, and they are often forgotten. Indeed, Coombs himself did not like the test being referred to as the Indirect Coombs Test and the Direct Coombs Test4, particularly as the principle of the test had been described in two papers published in the early 1900s,5, 6. 1. Coombs RRA, Mourant AE, Race RR. Detection of weak and ‘incomplete’ Rh agglutinins: A New Test. Lancet 1945, 246, 15-16. DOI: 10.1016/S0140-6736(45)90806-3. 2. Coombs RRA, Mourant AE, Race RR. A new test for the detection of weak and “incomplete” Rh agglutinins. British Journal of Experimental Pathology 1945; 26(4): 255-266. 3. Coombs RRA, Mourant AE, Race RR. In vivo isosensitization of red cells in babies with haemolytic disease. Lancet 1946; 247: 264-266. DOI: 10.1016/S0140-6736(46)91925-3. 4. Coombs RRA. Historical note: past, present and future of the antiglobulin test. Vox Sang 1998; 74: 67-73. DOI: 10.1046/j.1423-0410.1998.7420067.x. 5. Moreschi C. Neue tatsachen über die blutkörperchenagglutination. Zbl Bakt 1908; 46: 49-51. 6. Friedemann U. Weitere untersuchungen über den mechanismus der anaphylaxie. Z Immunitätsforsch Exp Ther 1 Originale 1909; 2: 591-641 (cited in reference 4).
  4. Welcome to this AMAZING site Jamie. ENJOY!
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  7. Welcome to this superb site BB1967. ENJOY!
  8. With a syringe and cannula I trust My Good Sir!!!!!!!!!!!!!!!!
  9. I confess that I am no expert on the chemistry of this, but, as I understand it from the late Prof. Patrick Mollison's book, it is purely to do with differences in the equilibrium constants of weak and strong antibodies.
  10. Welcome to this fantastic site AnnieHulk. ENJOY!
  11. Welcome to this marvellous site CBR. ENJOY!
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