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Malcolm Needs

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Malcolm Needs last won the day on September 20

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About Malcolm Needs

  • Birthday 12/14/1954

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  • Gender
  • Interests
    Rugby Union, Cricket, cooking, wine, port, reading, crosswords, lecturing, more wine and more port!
  • Biography
    Pretty boring really, but not that pretty!
  • Location
    Sourton, Devon, England
  • Occupation
    Prior to retirement, I had taken a brand-new role in the NHSBT and was involved very much more on the education and training side of red cell immunohaematology. My title was Reference Service Manager, but with Training after it (Reference Service Manager - Training). I was very excited about this change, as I have a passion for training and education.
    Reference Service Manager with the NHSBT.
    Ex-Chartered Scientist.
    Fellow of the British Blood Transfusion Society, having twice served on their National Council.
    Ex-Fellow of the Institute of Biomedical Science. Ex-member of their Special Advisory Panel for Transfusion Science and Chief Examiner for Transfusion Science for the Institute.
    Author of the chapter "Human erythrocyte antigens or blood groups" in Fundamentals of Biomedical Science, Transfusion and Transplantation Science, edited by Robin Knight, for the IBMS. 1st edition, Oxford University Press 2013 (ISBN 978-0-19-953328-2, pages 19-44.
    Was a member of the BSH Blood Transfusion Task Force (writing Guidelines).
    Member of ISBT and AABB
    I am now retired from the Blood Service, but still do the other things!
  • Real Name
    Malcolm Needs FBBTS

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  12. I would thoroughly recommend that you contact Rachel Moss Hibbttt at Imperial College Healthcare NHS Trust.
  13. Thanks gagpinks. Fine, but is the patient of anything other than (I'm not sure how to put this without offending people, but here goes) of pure UK ethnicity? As the patient is of child-bearing potential, AND is transfusion-dependent, I am CONVINCED that RCI should have taken the investigation further!
  14. Interesting case, and I agree entirely that the patient should be excluded from electronic issue, but how this decision be made known to any other hospital? I am somewhat surprised that the RCI Laboratory did not pursue the case further, unless no further samples were available, given that the patient underwent a classic acute haemolytic transfusion reaction, but I would also dispute that they tested the plasma against many (sufficient) low prevalence antigens. Of those you list, Do(a), Do(b), Lu(a) and Kp(a) would all be classified as polymorphic in the UK greater than1% expression in the population - although I fully realise that this classification is NOT the same throughout the world), and Co(a) is a HIGH prevalence antigen. In reality, therefore, the only low prevalence antigen against which they appear to have tested the plasma is Wr(a). It may be helpful in such a case to know the ethnicity of the patient, the sex and, if female, any pregnancies (and if these all went to term, or were any of the babies affected by HDFN), and, if the male partner is still available, whether or not his red cells could be typed and, possibly, tested against the patient's plasma (assuming for the moment, the patient is a female). I really am somewhat amazed that the RCI Laboratory did not submit a sample to the IBGRL.
  15. Welcome to this superb group QC3SD.
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