We have a patient with hereditary spherocytosis who is pregnant with twins who are due in a few weeks. We have been notified that the babies could require exchange transfusions due to hyperbilirubinemia from the spherocytosis if they inherit it. Does anyone have any experience with such a case? Besides small volume or exchange transfusions of one or more babies, mom is starting with a chronic anemia so will be in more trouble if she bleeds much. It will be a busy time if everyone needs transfusion, but I wanted to see if there are any concerns I haven't thought of. Fortunately, no antibodies and mom is A pos.