Patient Questions

Having a doctor when ever he requested for blood he insisted that same blood group should be giving to the patient even when the same group is not available in the fridge and when we wanted to give O, D positive blood he always refuses. Please any advantages of giving same blood group to patient and the disadvantages of giving O, D positive unit to the patient

Hello everyone, new to this forum. I work in hospital pathology lab in Australia- would love some advice on whether it’s necessary to transfuse only Group O red cells to patient’s that are probable A3 subgroup? I understand there is a small risk of A3 subgroups developing an allo-anti-A1, if transfused A1 red cells, but if their reverse group shows an absence of reactivity to A1 cells, is it necessary to restrict transfusion to only Group O? Has anyone also seen cases of loss of ABO antigen in Acute Lymphoblastic Leukaemia which can render false A1 negative subtype? Our patient’s forward group has mixed field reactions to 3 different monoclonal Anti-A anti s…

ALLOHOPEfoundation.org I just learned of this organization so wanted to share their name.

Help make sense of possibilities and if this is something to be of concern or not or if it could be a false positive: first pregnancy due in August - no previous miscarriages no blood transfusions etc. 2011 college class - did a lab and blood type was A+ (could have easily messed this up) feb 2020 pregnancy appt tested A- and negative for antibodies (13 weeks pregnant) June 2020 pregnancy appt tested A- but positive for “Passive anti D” antibodies (29 weeks pregnant) NOTE: doctors are super concerned and sending for ultrasound. Lab just assumed the result was expected because RHOGAM was given the same day BUT rho…

Hi, Hoping someone might be able to shed some light on the results from a 28 week prenatal blood test. My blood group is A Positive. As part of the standard testing they did an Antibody screening which came back abnormal. The Midwife told me it was for 'R1R1 K negative'. She said it was incredibly rare, and as she had only heard of 4 other cases with the same issue during her career, she was unable to give me any more information about it. Needless to say, I'm rather worried, even more so after consulting 'Doctor Google'. This is my first pregnancy and I have never received a blood transfusion. I remember reading about ABO and Rh incompatibility in school but ha…

Hello. I've had three early miscarriages. I have had positive antibody screens on the last two. My blood type is A positive. This is what the latest results says: "The patient's plasma contained warm autoantibody reactivity. Autologous adsorptions removed the autoantibody reactivity from the plasma. There were no alloantibodies directed toward the common blood group antigens detected in the autoadsorbed plasma. Incompatible crossmatches are likely with neat plasma. Eluate reacts with all cells tested." What does this mean? :) Do I need further testing? Thank you!!!!!

Hi Everyone, We did an IUT on a baby yesterday whose Mum has an anti-D quant of 847IU. Baby's pre-transfusion sample we tested on the Biovue card and the result was neg with the anti-A and anti-B but 4+ with the A,B. The D and the control well and DAT are also 4+. Any idea why the a,b is reacting with these cells? Thanks Kelli

Does a heterozygous HbSC patient need HbS negative blood?

Hi all, Considering that recently transfused/pregnant patients may potentially be developing a new antibody which may still be of the IgM type. How important is it to test sample @ RT (or use polysecific AHG reagent) especially for transfusion-dependent patients? Thank you

Hello, 28 y/o female, first pregnancy, O- blood type. Week 11 blood test labs indicated a weak antigen positive; unable to isolate. No bleeding during this pregnancy and no history of previous pregnancy/miscarriage. Due to this, I had never had a Rhogam shot. No previous blood transfusions. Based on my limited research (ie no access to academic articles, just the regular internet) this doesn’t seem right... Wondering if anyone could provide more insight into possibility of this being a false positive and/or explanation/commonality of this occurring? I will go back in at week 16 to do a second draw/retest. Thanks for any help/assistance/guidance.

I was recently asked how to manage a patient who is pregnant. I was told the patient is older and has had complications of which I was not told. The patient is not wanting to be transfused if PPH occurs. I can only think of TXA and Cell salvage for this patient to avoid blood transfusion during PPH. Do you have any other ideas? I did recommend VERY STRONGLY that they discuss their concerns with their physician! Thanks Teresa

Hi. I'm new here but was wondering if anyone can help me understand the following Lymphocyte Subset results as my consultant doesnt know what it means and my GP wont take it seriously and I'm fed up with being in severe pain with muscle weakness and a body that doesnt function on-going for 5 years with no help. I am a teetotaller and DO NOT drink ANY alcohol as I am allergic to it. All other tests in series ie FBC etc are in normal ranges I really do need help in understanding the following, where to go and what to do. Thanks. LYMPHOCYTE SUBSETS (TBNK) Type Result Range CD4% 63 H …

Hello, I am new to the forum! There's a case study at the hospital I work at and there's one question everyone's having trouble with. Patient is A pos and the question is "why are there reactions at immediate spin reading that do not show up at the AHG reading?". My first thought would be a cold antibody, but that typically has a reaction at immediate spin with a weak reaction at AHG, correct? What do you all think? Thanks!

What are other people's institutions practices on the following. If you have a patient with an anti-D do you need to go ahead and carry out the D antigen typing on the patients rbcs through the IAT phase(weak D testing)? The AABB 18TH ed. Technical Manual states on pg. 327 "When the D type of a patient is determined, a weak D test is not necessary except to assess the red cells of an infant whose mother is at risk of D immunization." It then goes on to say under Identification of Antibodies to Red Cell Antigens pg.401 "Determining the phenotype of the autologous red cells is an important part of antibody identification." We use MTS gel for as our primary method for bloo…

I just took over Blood Bank about 10 months ago, but I've worked nights for over 10 years, so it's been a long time since I've done Blood Bank. I have a 57yr old cancer patient who's typed B positive forwarding and reverse as AB. But we put it in the refrigerator for 15 mins and it came out a 2+ in the reverse. Never have had one like this before. What could cause?

I have been reading your threads about weak D and am thankful for the chance to ask questions of the experts. I will try to keep brief, but I am happy to answer any follow-up questions you have. Forgive my non-technical, common language. I hope my ignorance does not get in the way! I am 26 weeks into my fourth pregnancy (first one ended in miscarriage). For all of my pregnancies until this one (except for another exception I will explain) I have typed A+..."true" A+ with no weak D disclaimer. The exception I mentioned is one I just learned this morning, occurring in 2009 when I delivered my first-born via C-section. I was typed just before surgery as A-. M…

Hi, think this is my first post here. My name is Amy, just to share a tidbit with everyone.. I had a patient today that typed as such: Forward type: Anti-A = 2+ Anti-B = 4+ Anti-D = 4+ Reverse type: Acell = 0 Bcell = 0 Anti-A1 = 0 87 y/o male, oncology patient. I was reviewing reports for the BB Supervisor, when I saw the weak Anti-A in forward, I investigated and got the aforementioned results. The overnight tech released A+ blood on this patient, but no symptoms of transfusion reaction. I notified my pathologist and switched the patient to O+ in light of the absence of A1 antigens. my question: I am surprised to see that the A cell in the reverse type is…

Good afternoon, I am a pharmacist in Philadelphia and currently pregnant (4th pregnancy, will be 3rd child) and was wondering if you smart folks could help me understand some lab results I received better. My story goes as follows. I am blood type O- and my husband is O+. We have 2 children both of whom are O+ as well. With both of those pregnancies I received the anti D antibody injection at 28 weeks and post-delivery. I then became pregnant in December 2014 but started to bleed pretty heavily February 27th 2015 at 11 weeks along. I went to the hospital at that time and as of then the pregnancy was still considered viable (closed cervix and visible HB on ultrasound). At …

We have received one pregnant patient who had history of parabombay A (Ah-secretor). Four years ago, she was admitted for elective LSCS for her pregnancy.The blood group test done at that time showed forward reaction negative and reverse reaction positive to B cells (4+). The patient has received one parabombay A unit from her sister at that time. Recently, she was admitted for another LSCS and I was curious about the blood group testing. Her forward grouping was same, but reverse grouping showed 4+ reaction to A1 and B cells, 2+ to O cells. We used Bio-vue system for grouping. Antibody screening was negative. My question is the patient can actually develop anti-A1 antibo…

Hi, I have a question that has been covered in the forums about antibodies in pregnancy but I just wanted a little clarification. I have tested positive to anti e and anti cw at the 8 week blood test. This is my third pregnancy with the same father but it is the first time I have tested positive to these antibodies. My husband has tested negative in his screen and blood group test. Does this mean that there is now no risk to my baby? The Dr mentioned that I would still be high risk so am a little confused and would need monitoring but he did mention this wasn't his area. Any information/ knowledge will be greatly appreciated. Kelly

Hi, I would like to know the likelihood of a false-positive RH anti-bodies test 16 weeks after Rhogam. I found out I had a missed miscarriage at 12 weeks (baby stopped developing around 8 weeks) in October. I had a medically-induced miscarriage and received the Rhogam vaccine 8 hours after I started bleeding. This was my first pregnancy and I've never had a blood transfusion. I am O-, my husband is O+. I had a prenatal antibody test 12 week after receiving Rhogam and tested positive. I had a follow-up test 4 weeks later (16 weeks receiving the vaccine) and again tested positive. Unfortunately they have not given me my titer results and have told me to come back in 4 weeks…

forgive me if i put this in the wrong section! i am currently 11w3d pregnant, and my routine 8w blood work came back fine except on test found antibodies present in my blood. called me in for more blood. they asked if i have ever had a transfusion, which i have not. issued blood work for the baby's father, he is A+ and i am B+ so we are compatible. doc says it is the anti-cw antibody, and he would discuss more in depth at my next appointment, and i have heard nothing since. i can't find anything reliable or consistent on this, looking for any advice on what to expect? a nurse said im most likely going to be categorized as high risk and monitored but shouldnt worry too muc…

Hi If Anyone Could Help I Would Really Appreciate It. Pregnant Woman 17 Weeks Gestation, Routine Antenatal Screening Comes Back Immediately With Anti Cw Antibodies Detected And Needs The Patient And Her Partner Re Screened. How And Why Is This Done And What Could Have Caused It ?? The Patient Is A+ (rh D Pos?? ) We Think! Any Help Would Be Greatly Appreciated!!