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"Legal" release blood


pbaker

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From our P&P: "If a patient's life may be jeopardized by waiting the time necessary for completion and resolution of required pretransfusion tests, or if other conditions exist which create risks greater than those normally associated with transfusion, blood may be issued upon the request of a responsible physician, who then takes full responsibility for the consequences of the transfusion under those conditions." This would certainly qualify.

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We would use the term "least incompatible" on the consult form for the attending to sign only after determining that the problem with the crossmatch is likely due to a warm auto or something like that (that cannot be cleared up to our satisfaction).  The units themselves are recorded as "incompatible".

 

Scott

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Dave

 I don't like "least incompatible" either, but we only use it when the pathologist has consulted with the attending  about the impossibility of getting a "testable-compatible" unit for someone with a warm auto that cannot be cleared up, and must have a transfusion to survive.  This is pretty rare.  These units are actually recorded and tagged as "Incompatible".

 

Scott

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  • 3 weeks later...

Just as an aside to this - I was at a seminar where this topic was discussed.  The feelings were that if you can autoabsorb out the autoab and there was no evidence of sensitization to other blood groups, you could get by with just an immediate spin (and therefore compatible) crossmatch.  Kind of goes against the grain but makes sense too! 

 

Food for thought!

Edited by David Saikin
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involved with discussion: history of warm autoantibody, no alloantibody. Currently antibody screening is negative.

What do you do? Immediate spin crossmatch or extended crossmatch?

If the warm autoantibody is historical only and not detected on the current sample (current negative antibody screen, Gel method), we would revert to Computer Electronic Crossmatch/Electronic Issue.

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Our pathologist and the ordering physician must both approved transfusion.  The approval from the pathologist is usually verbal and is documented in the patient's history, as is the report from the reference lab regarding underlying alloantibodies.  The ordering physician must write a communication order that states "OK to transfuse least incompatible."  We use this terminology as it is usually a recommendation from the reference lab (the recommendation is preceded by the phrase, "If transfusion becomes necessary").

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We would call it "Least Incompatible", because we were told to do a complete XM on several units. We would usually see variance on the reactions and would pick the least incompatible units. We would do a complete XM with the non-absorbed  plasma, pick our least incompatible units, and complete XM with the absorbed plasma.

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Is there a Joint Commission or AABB standard that says you have to get a conditional release signed for 'least incompatible' blood?

Also, suppose you have a patient with warm auto-antibodies and no allo-antibodies. The patient is transfused and the subsequent specimen still has a positive antibody screen but at strengths not stronger than the pre-transfusion specimen, do you do the entire workout every 72 hours?

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