diplomatic_scarf 2 Posted May 18 We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai. Share this post Link to post Share on other sites
Malcolm Needs ★ 4,719 Posted May 18 Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus. 1 1 diplomatic_scarf and mrmic reacted to this Share this post Link to post Share on other sites
diplomatic_scarf 2 Posted May 18 20 minutes ago, Malcolm Needs said: Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus. Result: Patient red cells + Ulex europepeaus = Negative 1 Malcolm Needs reacted to this Share this post Link to post Share on other sites
yan xia 193 Posted May 18 (edited) or there are unexpected antibody/antibodies in the patient's plasma. Edited May 18 by yan xia Share this post Link to post Share on other sites
John C. Staley 1,091 Posted May 18 Have you attempted an antibody identification panel? Share this post Link to post Share on other sites
diplomatic_scarf 2 Posted May 18 56 minutes ago, yan xia said: or there are unexpected antibody/antibodies in the patient's plasma. That is what we are trying to figure out. Thank you Share this post Link to post Share on other sites
diplomatic_scarf 2 Posted May 18 4 minutes ago, John C. Staley said: Have you attempted an antibody identification panel? Result: Antibody identification panel: All panel cells = 4+ Auto-Control= Negative Share this post Link to post Share on other sites
Malcolm Needs ★ 4,719 Posted May 18 What you are identifying is almost certainly a strong anti-H in an Oh individual. However, if the individual requires a transfusion, you will need to perform differential allo-adsorption (or something similar) to identify any other underlying clinically significant atypical antibodies (you can ignore any underlying Lewis antibodies, which are commonly also present). 6 1 diplomatic_scarf, yan xia, exlimey and 4 others reacted to this Share this post Link to post Share on other sites
Malcolm Needs ★ 4,719 Posted May 19 3 hours ago, jojo808 said: Could have Anti-Jk3? Why would the red cells of an individual who is Jk(a-b-) not react with Ulex europeaus? 4 exlimey, Henrique, diplomatic_scarf and 1 other reacted to this Share this post Link to post Share on other sites
jayinsat 139 Posted May 19 On 5/18/2020 at 2:46 AM, diplomatic_scarf said: We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai. What is the patient's Rh type? 1 diplomatic_scarf reacted to this Share this post Link to post Share on other sites
LK11 13 Posted May 20 I agree with Malcolm, definitely looks like anti-H. 1 diplomatic_scarf reacted to this Share this post Link to post Share on other sites
Henrique 12 Posted May 20 6 hours ago, LK11 said: I agree with Malcolm, definitely looks like anti-H. And we need to remember: patient is from Mumbai. 2 Malcolm Needs and diplomatic_scarf reacted to this Share this post Link to post Share on other sites
diplomatic_scarf 2 Posted May 20 On 5/19/2020 at 6:57 AM, jayinsat said: What is the patient's Rh type? Anti-D + patient's red cells : 4+ Share this post Link to post Share on other sites
Malcolm Needs ★ 4,719 Posted May 21 12 hours ago, diplomatic_scarf said: Anti-D + patient's red cells : 4+ I can't say that I am in the least surprised about this, given the patient's ethnicity. There is a frequency of the D antigen of 99% in most Asian populations. 1 diplomatic_scarf reacted to this Share this post Link to post Share on other sites
