Posted May 18, 20205 yr comment_80253 We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai.
May 18, 20205 yr comment_80254 Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus.
May 18, 20205 yr Author comment_80255 20 minutes ago, Malcolm Needs said: Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus. Result: Patient red cells + Ulex europepeaus = Negative
May 18, 20205 yr comment_80256 or there are unexpected antibody/antibodies in the patient's plasma. Edited May 18, 20205 yr by yan xia
May 18, 20205 yr Author comment_80258 56 minutes ago, yan xia said: or there are unexpected antibody/antibodies in the patient's plasma. That is what we are trying to figure out. Thank you
May 18, 20205 yr Author comment_80259 4 minutes ago, John C. Staley said: Have you attempted an antibody identification panel? Result: Antibody identification panel: All panel cells = 4+ Auto-Control= Negative
May 18, 20205 yr comment_80263 What you are identifying is almost certainly a strong anti-H in an Oh individual. However, if the individual requires a transfusion, you will need to perform differential allo-adsorption (or something similar) to identify any other underlying clinically significant atypical antibodies (you can ignore any underlying Lewis antibodies, which are commonly also present).
May 19, 20205 yr comment_80268 3 hours ago, jojo808 said: Could have Anti-Jk3? Why would the red cells of an individual who is Jk(a-b-) not react with Ulex europeaus?
May 19, 20205 yr comment_80269 On 5/18/2020 at 2:46 AM, diplomatic_scarf said: We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai. What is the patient's Rh type?
May 20, 20205 yr comment_80276 6 hours ago, LK11 said: I agree with Malcolm, definitely looks like anti-H. And we need to remember: patient is from Mumbai.
May 20, 20205 yr Author comment_80279 On 5/19/2020 at 6:57 AM, jayinsat said: What is the patient's Rh type? Anti-D + patient's red cells : 4+
May 21, 20205 yr comment_80280 12 hours ago, diplomatic_scarf said: Anti-D + patient's red cells : 4+ I can't say that I am in the least surprised about this, given the patient's ethnicity. There is a frequency of the D antigen of 99% in most Asian populations.
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