diplomatic_scarf 14 Posted May 18, 2020 Share Posted May 18, 2020 We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai. Link to post Share on other sites
Malcolm Needs ★ 4,921 Posted May 18, 2020 Share Posted May 18, 2020 Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus. mrmic and diplomatic_scarf 1 1 Link to post Share on other sites
diplomatic_scarf 14 Posted May 18, 2020 Author Share Posted May 18, 2020 20 minutes ago, Malcolm Needs said: Looks like it could be an Oh individual. Try testing the red cells of the patient with Ulex europeaus. Result: Patient red cells + Ulex europepeaus = Negative Malcolm Needs 1 Link to post Share on other sites
yan xia 199 Posted May 18, 2020 Share Posted May 18, 2020 (edited) or there are unexpected antibody/antibodies in the patient's plasma. Edited May 18, 2020 by yan xia Link to post Share on other sites
John C. Staley 1,193 Posted May 18, 2020 Share Posted May 18, 2020 Have you attempted an antibody identification panel? Link to post Share on other sites
diplomatic_scarf 14 Posted May 18, 2020 Author Share Posted May 18, 2020 56 minutes ago, yan xia said: or there are unexpected antibody/antibodies in the patient's plasma. That is what we are trying to figure out. Thank you Link to post Share on other sites
diplomatic_scarf 14 Posted May 18, 2020 Author Share Posted May 18, 2020 4 minutes ago, John C. Staley said: Have you attempted an antibody identification panel? Result: Antibody identification panel: All panel cells = 4+ Auto-Control= Negative Link to post Share on other sites
Malcolm Needs ★ 4,921 Posted May 18, 2020 Share Posted May 18, 2020 What you are identifying is almost certainly a strong anti-H in an Oh individual. However, if the individual requires a transfusion, you will need to perform differential allo-adsorption (or something similar) to identify any other underlying clinically significant atypical antibodies (you can ignore any underlying Lewis antibodies, which are commonly also present). John C. Staley, diplomatic_scarf, exlimey and 4 others 6 1 Link to post Share on other sites
jojo808 53 Posted May 19, 2020 Share Posted May 19, 2020 Could have Anti-Jk3? Link to post Share on other sites
Malcolm Needs ★ 4,921 Posted May 19, 2020 Share Posted May 19, 2020 3 hours ago, jojo808 said: Could have Anti-Jk3? Why would the red cells of an individual who is Jk(a-b-) not react with Ulex europeaus? David Saikin, exlimey, Henrique and 1 other 4 Link to post Share on other sites
jayinsat 167 Posted May 19, 2020 Share Posted May 19, 2020 On 5/18/2020 at 2:46 AM, diplomatic_scarf said: We got a blood sample for ABO/Rh and Antibody screen testing. Results: Forward typing: Anti- A : Negative Anti-B : Negative Reverse typing: A1 cells: 4+ B cells: 4+ Antibody screen and auto-control: Cell 1: 4+ Cell 2: 4+ Cell 3: 4+ Auto-control: Negative Patient is from Mumbai. What is the patient's Rh type? diplomatic_scarf 1 Link to post Share on other sites
LK11 14 Posted May 20, 2020 Share Posted May 20, 2020 I agree with Malcolm, definitely looks like anti-H. diplomatic_scarf 1 Link to post Share on other sites
Henrique 12 Posted May 20, 2020 Share Posted May 20, 2020 6 hours ago, LK11 said: I agree with Malcolm, definitely looks like anti-H. And we need to remember: patient is from Mumbai. diplomatic_scarf and Malcolm Needs 2 Link to post Share on other sites
diplomatic_scarf 14 Posted May 20, 2020 Author Share Posted May 20, 2020 On 5/19/2020 at 6:57 AM, jayinsat said: What is the patient's Rh type? Anti-D + patient's red cells : 4+ Link to post Share on other sites
Malcolm Needs ★ 4,921 Posted May 21, 2020 Share Posted May 21, 2020 12 hours ago, diplomatic_scarf said: Anti-D + patient's red cells : 4+ I can't say that I am in the least surprised about this, given the patient's ethnicity. There is a frequency of the D antigen of 99% in most Asian populations. diplomatic_scarf 1 Link to post Share on other sites
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