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jojo808

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jojo808 last won the day on April 15

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  1. I think we need to add an OMG emoji to our selections!
  2. Some physicians are requesting that our IT build an Emergency release XM test to avoid having to sign 'the paper' for it. It will be a normal crossmatch test with the understanding that it is uncrossmatched and 'emergency released' via the verbiage that will be attached to it. Does anyone know if that is not acceptable to any agency? I will definitely require that the phone call to blood bank still be in the process, this is not my choice but I feel being forced upon us. I feel I'm the only one who objects to these things. Thanks in advance for the comments.
  3. When you say that the antigens are soluble and will inhibit the patient's anti-Lea in vivo, does that mean there will eventually be no Lea antigen on the donor rbc's? And let's just say it is certain that this patient has anti-Lea. Would there (theoretically) be no further problems with the first unit? or subsequent units?
  4. Fast forward: We think the cause of the incompatibility was (maybe) an Anti-Lea. We came to this conclusion because the 2 units that were clean were LeA negative and the other 2 that were reactive with the patient's plasma were LeA positive. This would be the only antigen that did not match the patient's phenotype. Anyway we are hoping our blood supplier can continue to get these (few) donors in. I think I've read in the past where anti-LeA is not clinically significant, but if this is an anti-LeA, it is not being detected by our ref lab who uses solid phase and tube. We use Ortho Gel (we do n
  5. So we did perform the tried and true tube method with Peg enhancement (actually our secondary method) and both units came out a clean negative. The MD wanted to transfuse only one unit and see how the patient does. I'm so ok with doing that. I will try and keep you all posted thank you all again.
  6. I apologize for the delivery of my plea. The patient only has anti-Jk3, anti-E, and anti-c period. The others listed is what he tests negative for regarding his antigen typing. Thank for for the quick responses, we will have a discussion with our pathologist and the patient's MD and decide from there. Malcolm I know you are retired but your expertise is welcome each and every time. I'm just wondering how to result our crossmatches. I guess we can result the units as "least incompatible" (because they are) and enter a comment on this sample such as " Phenotype matched (or identical) rbc's give
  7. Patient has the following antibodies: (Pt is B+) Jk3, E,c, He phenotypes K, Fya, S, N negative. Our ref lab found us 2 units that are phenotyped matched, one B+ and one O+ rbc. They are both incompatible, the O+ is 1+ in Gel, the B+ +/-. Auto control Neg, DAT neg (reference lab results). What's our next step??? BTW hope you all are doing well during this time.
  8. Forgive my ignorance but what is the positive reaction you get when testing reagent Anti-A with A2 cells due to??
  9. There is an article from George Garretty called Problems Associated With Passively Transfused Blood Group Alloantibodies that kind of mentions this. Although I feel it is perfectly safe to give out of group platelets, (we have done so for years) my concern was at what point would it interfere, if ever, with ABO/Rh type testing with tube method? According to the article worst case would be positive DAT but again I wonder if it would be detected in the plasma
  10. Hope someone can clear things up for me: 1. Can a type B recipient have 'testable' anti-B, acquired passively via transfusion of a few type A and type O platelets?? Let's say one out of type per day for a week. 2. Does Type B and Type O persons have naturally occurring Anti-A2?? Inquiring minds want to know, thanks in advance.
  11. Previous Quote from Malcom Needs while searching older content on this subject: "In most cases, TRALI is caused by donor leucocyte antibodies reacting with alloantigens present on the patient's leucocytes, although patient alloantibodies have been involved in some rare cases. The antibodies concerned are usually HLA class I and II specific, but HNA antibodies have also caused this". The thread was actually discussing solvent detergent plasma. When investigating possible TRALI, exactly what tests are usually ordered on the implicated donor? (Antibodies against HLA class I and II? And wha
  12. Just wondering why most use a 2nd sample only within 24 hours of collection. Does anyone see anything wrong with testing an older sample, say 3-4 days old??
  13. Does anyone audit the units transfused in the OR? How does the individual units transfused in the OR go into the patients record? Does the units go on a flow-sheet and someone transcribes this into the chart? Does the whole flow-sheet get scanned somewhere in the chart? I'm just trying to get as much information prior to a meeting about this. It seems like most are using coolers in the OR which seems 'more safe' than one refrigerator to 'share'. I'm willing to trust the process once it leaves the blood bank as long as that is compliant with AABB and CAP.
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