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"Sure it could happen ,,, and here's how... one of the parents perhaps has the Bombay phenotype"

or mum is a surrogate or baby is the result of an ivf with external donors

I am getting ready to install an ECHO Lumina. Just had our initial set up meeting yesterday. Switching from gel to solid phase. Looking forward to a bit more standardization in this department. We use DI but the ECHO also comes with its own middleware (or so I believe).

According to Human Blood Groups by Geoff Daniels, second edition, 40-42 Most B(A) have strong or normal B antigens, and most CisAB have weaker B antigens.

One person who I am very admired once said"There is no difference between CisAB and A(B)" I have the same question as Matthew. Since they have different names and there seems no intention to change, I guess there must be something different I do not know.

I'm chuckling reading all of this because it's like the question, 'If the parents are both Group O, can they produce a Group A baby?' Ask a student, they'll say 'No way!'. Ask a BB fanatic, they'll say, 'Sure it could happen ... and here's how ...' And in this forum, there is never a simple answer!

We used to CMV test our units and not add an additive solution. Our inventory (I suspect like most) is 100% leukoreduced, so that takes care of the CMV for us. We also allow Adsol units now, so we can easily get these from our supplier, just a regular O Neg less than 7 days old.

At one of my facilities we had a group of O neg donors that would come in on a regular basis and these folks were designated as out Neonate Donors. I think at the time we would set them aside exclusively for the neonates for a week and if they were not needed during that week we would move them to the general population. We would ask regular O neg donors if they could come in on a schedule so they could be used for the babies. When most understood that their blood would be designated for the newborns little else had to be said to get them on board.

We have two IH 1000. BioRad has been great to work with. They are workhorses. They are complicated and tend to have a fair amount of downtime. Many years ago when we first introduced automation it was solid phase. A lot of our patients were then coming up D positive (D neg history) as the methodology was a lot more sensitive than tube. The same thing happened a few years ago when we switched to gel. You'll also pick up more colds and junk with gel. Overall we're happy. We might consider an IH 500 someday for the titers.

Malcom is, of course, correct. Epic is a hospital information system/electronic medical record. They have a laboratory module called Beaker, but do not have a blood bank information system. Epic users have to integrate a stand-alone B.B. system (Meditech, SoftBank, Sunquest, etc...) with it. Epic has a blood product administration module (BPAM) that allows electronic scanning of patient and unit at the bedside (in lieu of paper records). It’s not really fast enough for a massive transfusion situation at this point so we struggle to find an alternative in the most stressful times. Rover i