jnadeau

Thank you ALL for your insightful posts - my student is a little overwhelmed with some of the replies (and might be sorry she asked) but she's very sharp and also appreciates your expertise - it's led to some thoughtful discussions here. Since we would have a negative antibody screen performed shortly before they would give a RhIG shot and since we "rule out" some antibodies without respect to dosage when performing an antibody screen I think we'll continue with the abbreviated panel in these instances. Happy Holidays to you all.

Thank you all but I still can't find a reference for acceptably using an abbreviated panel (Ortho 0.8% panel) to rule out other clinically significant antibodies on the panel when passively acquired Anti-D is suspected (i.e. a negative antepartum antibody screen and documented administration of RhIG)

Thank you Malcolm. Just to clarify, this abbreviated panel is done only when the prenatal antibody screen was negative and a RhIG shot has been verified as given.

On the topic of passive antibodies, I have a student in transfusion services right now who wants to know why we don't have to respect zygosity when ruling out on an abbreviated panel (Ortho 0.8%) performed when passively acquired anti-D is suspected to be the reason for the positive antibody screen. I have emphasized the importance of ruling out using zygosity or possibly missing an antibody. Now with the abbreviated panel I tell them ruling out with zygosity is not necessary. Anybody have any history on this?

Sorry no, I'm not that clever Mable. Came across it a while ago (2009) researching best practices on consents to update our P&Ps. Obviously it's much older with that language (wantonly!). Maybe some youngster can find out. My search engine is tired.

I came up with the attached and had them laminated and distributed to every unit - can't confirm that the info is always presented in full but...all we can do is try to help.informed consent2.docinformed consent2.docinformed consent2.doc

A gentleman and a scholar (and a natural comedian). Thanks for sharing your knowledge in such an understandable way through the years - and now with this pic I can point to my reference! Congrats again

Will you please post a picture receiving the medal - then when I quote you I can show them my reference! Congrats Malcolm!

After being cited by a NYS inspector a few years ago for vital signs not being documented as described in the blood administration policy (some pre- and post vitals were documented with the same time as the start and end times) I searched through numerous P&P's and regulations from around the world (English speaking anyway) to find a fix. The citing was legitimate (pre=BEFORE START, post....) and I wanted the corrective action to reflect the most up-to-date best practice I could find. There was an almost universal policy/regulation for pre-, 15 min and post vital signs. The variations in the timing of vital signs (other than the 15 min ) was all over the map. The multitude of situations patients are in make it difficult to be cut and dry in a P&P. Decided to go with pre- and post within 30 min of start and stop; must stay with patient first 15 min so that was easy. More frequent vitals if provider indicated (almost never) or transfusionist deems patient requires - or if I recommend with my knowledge of the patient history / lab results. You know though, that as soon as there's an incident they'll "fix" it by requiring more frequent vitals and the loop continues...keep your old policy handy.

I have noticed this too, more recently in the past couple of years - they're coming up in gel which we know enhances the "M"s but...why enough times to take notice now? We report them as a cold autoantibody mimicking anti-M. The providers never call to question this ...aren't you surprised?

I've taken an outpatient sample (so I know it won't be needed again), added 3 drops of anti-s (BioRad - IAT), mixed and put it in the water bath agitating for about an hour. Works like a charm. I've also used Coombs control (labeled as a patient sample) - they elute anti-D as expected-much less of an eluate volume but we use gel so there's enough.

Thank you very much Malcolm. I'm going to read this over again at home - maybe with a cold beverage in hand - and let it sink in. I appreciate the time you take to answer these questions and my student will be very pleased with your compliments.

My student asked about the original natural antibodies in the plasma - I assume they're "wiped out" with patient's B cells in the chemo/radiation and the transplanted B cells in the donor's marrow makes the appropriate antibody(ies) for the patient's new blood type. What about the tissue/organs that express ABO antigens though? Please help Malcolm.

Sorry but the "Help" content at the Emergency Issue for Products prompt says that the system references this prompt only if the patient has no current blood type - if the patient has a blood type history that would normally be considered incompatible with group A FFP the system puts a hard stop on it.

Does anyone know of a dictionary setting in Meditech 5.67 that will allow emergency release of group A FFP/FP? I've looked in Meditech's "knowledge based" articles but...nothing found. I don't want to change the blood group settings dictionary - just want to be able to override the pop-up for this blood type and product. Paper (as in downtime) is the only option I can think of with this old mind - and in an emergency setting that is not ideal.