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Townsend

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  1. Like
    Townsend got a reaction from John C. Staley in Need Advice   
    The last time we saw this at our institution, the ECMO team found a crack in the cannula!!! I agree with Yanxia - the clinical and surgical team needs to check the ECMO circuit for causes of mechanical hemolysis and lines.  Our team had to redo the cannulas and circuit in this case and the hemolysis went away as soon as that was completed.
  2. Like
    Townsend got a reaction from SbbPerson in Rh genotype   
    We would honor the molecular typing and provide E-, c-, and K- red cells for this patient moving forward.  Your serologic typing results are not valid due to recent transfusion, and this isn't an uncommon genotype for a thalassemia patient.  Unfortunately this means that the patient received c pos units (when you gave C-, K- red cells), but that was the best you could do without knowing that information before the first transfusion was ordered at your facility.  We come across this frequently with new/relocated sickle and thalassemia patients.
  3. Like
    Townsend got a reaction from SbbPerson in HemeLabTalk: HbF   
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    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Bombay phenotype   
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    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Knops Blood Group System   
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    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Monospecific antibody   
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    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Diego Blood Group System   
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  9. Like
    I agree with Bet'naSBB - the IS XM must be done in either tube or gel/other serologic method to verify ABO compatibility.  Since a patient with a current or history of clinically significant antibody does not qualify for electronic crossmatch, the serologic version must be included with the AHG phase XM.
  10. Like
    I agree with Bet'naSBB - the IS XM must be done in either tube or gel/other serologic method to verify ABO compatibility.  Since a patient with a current or history of clinically significant antibody does not qualify for electronic crossmatch, the serologic version must be included with the AHG phase XM.
  11. Like
    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Correct Blood Bank Nomenclature   
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    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Correct Blood Bank Nomenclature   
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  13. Like
    Townsend got a reaction from Kelly Guenthner in Ortho MTS old centrifuge and heat block   
    Following - I am so glad you asked this question as I have asked the same thing to both Ortho and AABB with no direct response.
    My question was, is there a requirement for an incubator and centrifuge to be an FDA cleared medical device?  We use them throughout the lab and blood bank for specimen centrifugation and for serologic tube testing, and those are not FDA cleared devices.  As long as your equipment is maintained and is meeting the requirements of the circular/instructions for use, aren't you compliant?
     
  14. Like
    Townsend got a reaction from exlimey in Ortho MTS old centrifuge and heat block   
    Following - I am so glad you asked this question as I have asked the same thing to both Ortho and AABB with no direct response.
    My question was, is there a requirement for an incubator and centrifuge to be an FDA cleared medical device?  We use them throughout the lab and blood bank for specimen centrifugation and for serologic tube testing, and those are not FDA cleared devices.  As long as your equipment is maintained and is meeting the requirements of the circular/instructions for use, aren't you compliant?
     
  15. Like
    Townsend got a reaction from applejw in Ortho MTS old centrifuge and heat block   
    Following - I am so glad you asked this question as I have asked the same thing to both Ortho and AABB with no direct response.
    My question was, is there a requirement for an incubator and centrifuge to be an FDA cleared medical device?  We use them throughout the lab and blood bank for specimen centrifugation and for serologic tube testing, and those are not FDA cleared devices.  As long as your equipment is maintained and is meeting the requirements of the circular/instructions for use, aren't you compliant?
     
  16. Like
    Townsend got a reaction from Mabel Adams in Proficiency Testing for TEG 6s   
    There is a CAP proficiency code "VES" (viscoelastic testing) for TEG and ROTEM testing.
  17. Like
    Townsend got a reaction from Malcolm Needs in BloodBankTalk: Correct Blood Bank Nomenclature   
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  18. Like
    We are only doing Anti-A and Anti-B titers at this time (pediatric facility, so we aren't doing prenatal titers).  I'm not sure what version of software you all are on, but when we went live with our titers on the Vision Swift and latest software version, there is a glitch in the serial dilution setup.  We have to skip the 1:1 on both IgG and Buffered Card titers (doing that on the bench) and then only setup the 1:2 to 1:1024 on the Vision or we get errors.  The Vision will keep trying to setup the dilution series, getting all the way to the end where it pipettes the 1:1 in the cards, and then abort the entire test.  Then it tries over and over again to set up the dilution, and repeats error/setup until the sample is all used up.  I sure hope this gets fixed soon - if you do titers, reach out to QuidelOrtho before taking the latest software update!!!!!!
  19. Like
    Townsend got a reaction from DonnaT in Vision DAT testing   
    We run our Poly and IgG DATs on the Vision.  We make up our own in-house pos/neg DAT samples as recommended by the Ortho rep.  Here is our procedure to prepare those tubes and labels below.  If you don't have an SCD, you might be able to enter a unit that was expiring, but you'd have to establish some sort of expiration for the cells/sample then:
    1.   Select an Rh Positive red cell unit with a good outdate from the available inventory.
    2.   Complete a label with the lot “DPMMYY” (using MMYY as the month and year of preparation; i.e. “DP0521”).  Add the expiration date equal to the expiration date of the red cell unit as well as the date prepared and your initials.  Place a barcoded P10000 LIS accession label on the vial so it can be scanned onto the Vision.
    3.   Complete a label with the lot “DNMMYY” (using MMYY as the month and year of preparation; i.e. “DN0521”).  Add the expiration date equal to the expiration date of the red cell unit as well as the date prepared and your initials.  Place a barcoded N20000 LIS accession label on the vial so it can be scanned onto the Vision.
    4.   Connect a syringe set to the red cell using the Sterile Connection Device and remove approx. 10mL of packed cells.  Place the red cells evenly into two plastic 12x75mm test tubes (one labeled P10000 and the other with the N20000 label made above).
    5.   Add 2 drops of Anti-D (Ortho Bioclone) to the P10000 packed cells, mix well, and incubate for 30 minutes at 37°C.  Mix again about half-way through incubation.
    6.   Test each of the prepared red cells by performing a Poly DAT in gel on the bench.  Ensure that the results are 1-3+ on the P10000 cells and negative on the N20000 cells prior to placing the vial into use.
  20. Like
    Townsend got a reaction from AuntiS in Antibody Titers Gel vs. Tube   
    We do our titers in gel (ABO titers only as we are not a delivering hospital; pediatric only).  Any positive reaction seen in gel should be interpreted as 1+ since there is no w+ interp in the MTS gel interp. guide - there is also no w+ on the Vision.  So, our end-point is the dilution with the last 1+ positive. Our results have correlated well with the CAP samples done in tube when looking at all of the methods reported, but we have only done these for about a year now (only about 3 CAP survey's so far).
    We haven't looked at bringing this onto the Vision yet..... all though I am aware that it is now able to do the dilutions for both the buffered card and IgG titer reactions; so maybe with the next software upgrade???  Would love to hear back if you successfully implement the titers on the Vision!
    Stephanie
  21. Like
    Townsend got a reaction from R1R2 in LISS Validation?   
    Yes, you should do at least a small parallel study using the old and the new.  Your director will have to decide on how many would be acceptable and define acceptability criteria prior to implementation.  I would summarize and have them sign-off before placing it into use.
  22. Like
    Townsend got a reaction from AMcCord in LISS Validation?   
    Yes, you should do at least a small parallel study using the old and the new.  Your director will have to decide on how many would be acceptable and define acceptability criteria prior to implementation.  I would summarize and have them sign-off before placing it into use.
  23. Like
    Townsend got a reaction from David Saikin in LISS Validation?   
    Yes, you should do at least a small parallel study using the old and the new.  Your director will have to decide on how many would be acceptable and define acceptability criteria prior to implementation.  I would summarize and have them sign-off before placing it into use.
  24. Like
    Townsend got a reaction from carolyn swickard in PAS C platelets and Neonates   
    Pediatric hospital - we have been transfusing both PAS and pathogen-reduced platelets to our patients since April of this year, including neonates.  We have only had one minor allergic reaction reported from PAS to date, and it was an older patient (teenager).
  25. Like
    Townsend got a reaction from AMcCord in PAS C platelets and Neonates   
    Pediatric hospital - we have been transfusing both PAS and pathogen-reduced platelets to our patients since April of this year, including neonates.  We have only had one minor allergic reaction reported from PAS to date, and it was an older patient (teenager).

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