As of right now we do not QC our panels, we have both Gel and Tube panels and we do QC out gel and tube screening cells. I went through our different manufactures panel IFU I have the following questions and thoughts. Ortho says "should be tested periodically with weak antibodies" 1) What is periodically? Defined as repeatedly at regular time. Is this once for each panel? or one a day, week, month or year? Or what? 2) Weak, how weak 1+? 3) Antibodies - how many, all of them? Only clinically significant or what? Bio-Rad says "Suitable controls should be included in each test run." 1) Each test run? Meaning with each panel run? That could be a couple times a day.... Immucor - Says “the reactivity of the red blood cells may be checked periodically by testing antigens likely to deteriorate, such as Lea, with a weakly reactive antibody of the same specificity. Still says periodically but is more specific about the antibody. Quotient-Alba says "Quality Control is essential and should be performed in accordance with local, state and federal regulations. This one is wide open