Use of LipoClear on BBK blood samples

[Dansket]

Has anyone used this solution, that is used for clearing lipemic blood samples in Chemistry, in Blood Bank?

LipoBrochure.pdf

Edited December 4, 2015 by Dansket

[Malcolm Needs ☆]

No.  I didn't even know it existed.

[David Saikin]

You'd really have to validate that it did not disrupt immunoglobulin . . .

[amym1586]

That would be pretty cool if we could.

[Dansket]

I've attached their brochure to my original post.

[AMcCord]

We do use this stuff in Chemistry. Before I though about using it in Blood Bank, I'd contact the manufacturer to see what type of interference the product can cause and ask if they did any testing for blood bank specimens. My bet is that they have not done any kind of validation for blood bank and there is no clearance for that use. Which means....validation would be on you. I think it would take pretty extensive validation with as many antibody specificities as possible plus the backtypes for variant ABOs. I don't think I'd touch it. Admittedly, we don't see a whole lot of specimens that won't run on the Echo because of lipemia. Those few that do show up are tested in tube.

 

[tbostock]

When we validated our Tango we put a sample on that looked like heavy cream.  It resulted beautifully.

[AMcCord]

16 hours ago, tbostock said:

When we validated our Tango we put a sample on that looked like heavy cream.  It resulted beautifully.

We've also run some pretty creamy looking samples on the Echo w/o problems. I've had 2 samples that were too nasty for it in the last 7+ years. Very very lipemic.

[AuntiS]

We use it in Chemistry here as well.  Never thought of using it any where else!  Never had the need for it...

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[Auntie-D]

I've never yet had a blood bank sample where lipaemia has been an issue. I can't see it being 'allowed' based on laboratory validation alone as there is too much risk of it knocking off antigen sites.