NAN47 25 Report post Posted July 21, 2014 Hi there, I was hoping that someone could help me out with the following grouping anomalies and what their interpretation is. 1)what group would this be - reaction with anti-A -4+, Anti-B - neg, PVP-neg, A1 cells - 2+, B cells 4+ and O cells - 2+ 2)what causes this? reaction with anti-A - 4+, Anti-B -1+, PVP-neg, A cells- neg, B cells-4+ and O cells-neg. thanks Tricia Share this post Link to post Share on other sites
David Saikin 1,148 Report post Posted September 4, 2015 1 - a cold agglutinin - could have specificity (I,M) or not. would like to see an auto control 2. looks like an acquired B (if an old specimen out of the frigde or could be a weak subgroup of B (kind of rare). 2 galvania and Malcolm Needs reacted to this Share this post Link to post Share on other sites
Malcolm Needs ★ 3,765 Report post Posted September 4, 2015 I agree with id, BUT the monoclonal anti-B reagents produced these days are selected specifically so that they do not detect acquired-B. Was this a study question by any chance???????????? Share this post Link to post Share on other sites
David Saikin 1,148 Report post Posted September 8, 2015 I wondered that myself Share this post Link to post Share on other sites
EDibble 68 Report post Posted September 25, 2015 I agree with Malcolm and David. Have seen this several times. Share this post Link to post Share on other sites
