Hi there, I was hoping that someone could help me out with the following grouping anomalies and what their interpretation is.

 

1)what group would this be - reaction with anti-A -4+, Anti-B - neg, PVP-neg, A1 cells - 2+, B cells 4+ and O cells - 2+

 

2)what causes this?  reaction with anti-A - 4+, Anti-B -1+, PVP-neg, A cells- neg, B cells-4+ and O cells-neg.

 

thanks

 

Tricia

1 - a cold agglutinin - could have specificity (I,M) or not.  would like to see an auto control

 

2.  looks like an acquired B (if an old specimen out of the frigde or could be a weak subgroup of B (kind of rare).

I agree with id, BUT the monoclonal anti-B reagents produced these days are selected specifically so that they do not detect acquired-B.  Was this a study question by any chance????????????

I wondered that myself

I agree with Malcolm and David. Have seen this several times.