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yan xia

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yan xia last won the day on December 16 2018

yan xia had the most liked content!

About yan xia

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    Seasoned poster
  • Birthday 08/25/1982

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    reading, travel,talk with a good friend et al.
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    bloodtransfusion department in hospital
  • Real Name
    Yanxia Wang

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  1. I have met two cases of babies. Their plasma had anti-A or anti-B, as their correspond type. And the doctors had not seen HDFN signs clinically. We found it through crossmatch.( we issue same type blood to infant have no ABO HDFN).
  2. The baby's DAT is negative. Yes, the baby has anaemic and very bad sicked on the machine to help him breath. He has very servere infection, maybe this cover the symptoms which shows HDFN. And ABO HDFN is always mild. The jaundice is normal.
  3. My experience and knowledge in bloodbank is so little. This is the first time I met an warm reactive anti-A1 and which can pass the placenta barria. It is new to me.
  4. Sorry , I cannot sure about that. Is there IgG anti-A1 exist in subgroup people?
  5. I just encounter a 3 days old baby, his type is A pos, and has anti-A in his blood. His mom is A subgroup B. If the baby have anti-A, it is IgG. Is it possible an A sub B produce IgG anti-A? Thanks for your advise.
  6. If the reverse reaction with B cell was a typo, I agree with Malcolm, it is an anti-A1or anti-ALeb. As for the negative saline replacement result, since the neat plasma reaction is weak, it maybe weaken by the test method.
  7. If the patient has received transfusion, the transfused antigens pos cells can cause the autocontrol mixed field positive, and when the antibodies are against some low prevalence antigens, then the reaction with screening cells and donor cells can get a neg reaction. Or some drug induced antibodies can cause this kind of reaction because they are drug dependent.
  8. Sorry, I am stubborn as for this major, I guess I have caused noise here. If the reverse type show antibody then it is ok, why would we call 2+ or more to be normal and less to be weak and then to invest it? For ABweak patients, I still think it is safe to transfuse them with AB plasma, even they have their anti-B ,but the anti-B is not the same as O and A people's, it is not react with its own B antigens, but the transfused anti-B can, that is why the weak B antigen can be detected with some strengthen method. We will identify this kind of weak antigen with add more serum ,4 degree C incubation or adsorption/elution test, not genotype it, which is not so expensive.
  9. I totally agree with you about the transfusion, galvania. And I think we should call it AB subgroup if there are weak B antigens, rather than A group, because sometimes they will need plasma and something contains plasma.
  10. In the case of ABel, the forward typing is not shown B antigens, and reverse typing with weaken anti-B.
  11. This is my understanding, maybe it is not correct, just want to share it here, and correction is always welcomed. If the reverse typing is weak than 2+, it means the immediate spin result, the antiboies are weaker than normal, subgroup or weaken antiglobulin. Even we incubate or change the reaction temperature or add more serum, it shows 2+ or stronger reaction, it is still weaker than normal typing( not so exactly, because my Enligh is not good). Can we call it normal when we incubate or 4 degree C treaction 2+, no. These are just ways to strengthen the reaction. Which is somehow like we do weak D test, can we call it normal D when we get pos result in anti-antiglobulin test.
  12. I agree with you if transfusing RBCs, on the other hand, plasma transfusion, I think it is safe to test if the weak B antigens exist or not.
  13. I would add more antisera and/ or incubate the forward test at 4 degree C to see if there are B antigens here, if negative then adsorption and elution on the forward B antigens to see if it is existed. The most important thing as Malcolm mentioned above keep a group O cell as negative control. If all the above tests are all neg, then I will call it A type with weaken anti-B.
  14. Sir

    would you please send me a copy of the PPT , this is my email address shilysunny@foxmail.com

    thank you very much

  15. I think washed out the plasma and freed K+ is safer to newborn, and it is not too expensive, just 20 yuan more than the packed cells. And if do the anti-A, B titre in the packed cells is also time consuming and money consuming. Just my personal opinion.
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