gagpinks

I just answered this question. My Score PASS  

we did try this but apparently, it works very weekly than expected.

As Bankergirl mentioned you can use IAT method to confirm. But it will not differentiate between partial D and weak D

Hi I was reading articles on social media regarding 2-year-old girl developed anti-Inb ( In a news article from the USA). She has neuroblastoma and difficulty finding Inb negative blood. If a patient is on chemotherapy and required regular transfusion it is hard to provide blood in these situations. How severe anti-Inb can cause transfusion reactions especially when a patient is on chemotherapy? Can she have ABO and D compatible blood with methylprednisolone?

Reviewing this process so just wondering did you use any control with this process? Do we need to run control ? Can't find in guidelines

This could be due to anti c IgM in nature. I have seen this many time especially in pregnant lady.

Do you run any control with this process ? With IAT crossmatch we use OR1r cell with weak antiD.

Hi Does anyone use immediate spin method for crossmatch? Do you require any control in this process? I personally don't prefer this method especially when you have robust IT system and 2 sample policy.

Welcome Rupalben!!

Hi thanks for your reply First Virginia then after while probably Texas

Another interesting similar case. In this case antibody screen negative in first pregnancy and also negative at booking blood in second pregnancy. Repeat antibody screen at 28 weeks found to be positive with anti-c . There is also additional reaction detected in reverse group probably due to Anti- c IgM in nature . Send sample to RCI and quantification level is 37.2 IU/ml and followed repeat testing in 2 weeks went up to 56. Clinician decided to induce her at 36 week. First baby was Rh negative now just waiting for baby to born. Hope baby is not r'r . Otherwise it will be real challenging scenario.

Thank you for your reply. I guess i was being over cautious. We trust RCI result but my worry was if we x match at our hospital it will be definitely incompatible (2 or 3+). I was over thinking that we could have missed out low frequency antibody. Just out of curiosity if we perform x match at RCI do you treat Donor cell with DTT. Of just issue least incompatible unit.

Thank you galvania. But what does your lab usually in terms of X match. Because if we perform xmatch its seems pointless because it would be positive. How can we ensure that units are compatible?

If patient is on Dara is it safer to ask reference lab to perform X match or we can x match onsite once it's confiremed by RCI that there is no underlying alloantibody.

I guess it's applies for transfusions as well. If I want to work in blood bank do I need to pass any exam ?