Posted February 27, 20178 yr comment_68935 When performing compatibility testing with a patient who has Anti-A1, do you do a full cross match (through AHG phase) with the donor units?
February 27, 20178 yr comment_68937 I would certainly perform tests at 37oC, just to see if the anti-A1 is one of those exceedingly rare examples that may be clinically significant. If these tests are negative, I would not bother to go to the AHG phase.
February 27, 20178 yr comment_68938 3 minutes ago, LIMPER55 said: Yes because lis makes us but we crossmatch type O What makes you? If it is your computer programme, I would urge that you change your computer programme so that it only makes you when the anti-A1 genuinely reacts at 37oC (pre-warmed, etc). A computer in the laboratory is there to aid the staff; not to make things more difficult.
February 27, 20178 yr Author comment_68939 Our Lis does not flag. We rarely seem them. But I'm not even sure the LIS will flag if the donor selected is not O pos. I was curious so I could set up our LIS correctly. We have Soft, I'm not too fond of the Softbank portion of it. Thanks for you input
February 27, 20178 yr comment_68941 Well, unless the anti-A1 really is one of the exceedingly rare clinically-significant ones, reacting at STRICTLY 37oC, the donor does not have to be group O - indeed, unless the anti-A1 does come into this incredibly rare type, you can very safely give blood from an A1 donor.
February 28, 20178 yr comment_68951 That makes sense, Malcolm, and I agree - but then there's that pesky IS incompatible crossmatch... Generally speaking, my techs don't like an IS incompatibility! So we give O. Or B, if the patient is AB.
March 2, 20178 yr comment_68972 For years, we had a policy for determining the 37C reactivity, but we had a lot of generalists rotating through Blood Bank & there was no time to document their competency on a test they might do once in a great while. So, we went with B for AB and O for A. We were a small hospital & I determined it was only about 10 extra O units a year.
Create an account or sign in to comment