SMILLER Posted February 11, 2015 Share Posted February 11, 2015 Does someone know of a link to a one or two-page Antigen Chart? You know, one that lists antigens, thier reaction characteristics, and how common they are? We have a big chart, but it would be nice to have a smaller one that we can stick up in our student cubby, so when we ask inpertinent questions like "how many units are you going to have to screen in order to get two compatable...", they can do the math. Thanks Scott Link to comment Share on other sites More sharing options...
Auntie-D Posted February 11, 2015 Share Posted February 11, 2015 Ooo I can help with that! I'll dig mine out and attach it later Link to comment Share on other sites More sharing options...
Auntie-D Posted February 11, 2015 Share Posted February 11, 2015 Found it!Antigen_specificity_and_blood_selection1.docx mollyredone, L106 and R1R2 3 Link to comment Share on other sites More sharing options...
SMILLER Posted February 11, 2015 Author Share Posted February 11, 2015 Awesome! That looks pretty good! Thanks alot! Scott Link to comment Share on other sites More sharing options...
Eagle Eye Posted February 12, 2015 Share Posted February 12, 2015 Found it!Anti-f may mimic Anti D+C with C showing higher dosage – can cause DHTR and HDN Please check the note at bottom..........Isn't anti-f is combination of anti-c+e? Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted February 12, 2015 Share Posted February 12, 2015 You are perfectly correct in one way Eagle Eye, except that anti-f is not a combination of anti-c+e, but a compound anti-ce - in other words, it will react with a ce antigen on the same haplotype (such as dce or Dce), i.e. when, for want of a better way of putting it, the RHc and RHe genes are in the cis position, but will not react with red cells when the c and e antigens are derived from different haplotypes (such as DCe/DcE), i.e. when, for want of a better way of putting it, the RHc and RHe genes are in the trans position. All that having been said, however,it is a typographical error anyway, as it should read, "anti-G may mimic anti-C+D, with the anti-C normally showing stronger reactions than the anti-D." Unfortunately, although citing an NHSBT Document at the bottom (SPN/DDR/RC/020/02), this is not from the actual document (which is 33 pages in length, which has just been updated by the author - Dr. Geoff Daniels on 12 January 2015 - and which does not contain this table). Link to comment Share on other sites More sharing options...
Auntie-D Posted February 12, 2015 Share Posted February 12, 2015 (edited) You are both right - it was a typo sorry Double typo I had added it after a patient had a DHTR due to anti-f in flying squad units. Edited February 12, 2015 by Auntie-D Link to comment Share on other sites More sharing options...
Dr. Pepper Posted February 12, 2015 Share Posted February 12, 2015 Auntie, that's a nice chart. One question: at the bottom of the red Antibody column on the left, below anti-Lub, there's an entry "Active @37oC" What is this refering to? Undetermined antibodies to low incidence antigens? Thanks - Phil Link to comment Share on other sites More sharing options...
Auntie-D Posted February 12, 2015 Share Posted February 12, 2015 Auntie, that's a nice chart. One question: at the bottom of the red Antibody column on the left, below anti-Lub, there's an entry "Active @37oC" What is this refering to? Undetermined antibodies to low incidence antigens? Thanks - Phil Yup, but there wasn't enough room Link to comment Share on other sites More sharing options...
Moncada Posted February 12, 2015 Share Posted February 12, 2015 Also curious about the frequency column, assuming this is the freq. of compatilbe units, I think k(cellano) and Kpb frequencies are in error. The frequency listed for these 2 antibodies reflects the "incompatible" rates. Link to comment Share on other sites More sharing options...
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