Halima Posted May 15, 2012 Share Posted May 15, 2012 Hi A pateint with macrogloubulinaemia, and has a strong IgM in his blood which didnt go with prewarmed tube method, I cant find compatible blood,, all the tests show strong agglutination even before adding AHG reagent,, we dont have DTT reagent to remove IgM from the plasma,,we transfused the patient with uncompatible but Rh group matching blood units a week ago and afraid that the patient developed alloantibodies,,, any ideas to how to remove IgM from the plasma:(:( Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 15, 2012 Share Posted May 15, 2012 If you haven't got access to DTT, have you got access to rabbit erythrocyte stroma? Link to comment Share on other sites More sharing options...
Halima Posted May 15, 2012 Author Share Posted May 15, 2012 If you haven't got access to DTT, have you got access to rabbit erythrocyte stroma?No am afraid not,,, Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 15, 2012 Share Posted May 15, 2012 Hmmmmmmmm.............I'll have to think about this one, but nothing comes immediately to mind, except to send it to your Reference Laboratory. Link to comment Share on other sites More sharing options...
MAGNUM Posted May 16, 2012 Share Posted May 16, 2012 No am afraid not,,,Immucor has a product that uses rabbit erythrocyte stroma called REST for removal of colds Link to comment Share on other sites More sharing options...
Barbarakym Posted May 16, 2012 Share Posted May 16, 2012 We send stuff like this to reference labs. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 16, 2012 Share Posted May 16, 2012 Immucor has a product that uses rabbit erythrocyte stroma called REST for removal of coldsThat's the one I meant; just couldn't remember who made it. Link to comment Share on other sites More sharing options...
bmarotto Posted May 16, 2012 Share Posted May 16, 2012 That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 17, 2012 Share Posted May 17, 2012 That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own.Now there's a thought........................cheaper! Link to comment Share on other sites More sharing options...
Rh-fan Posted May 17, 2012 Share Posted May 17, 2012 That is a relief Malcolm. I had visions of you hunting down little bunnies and making your own.I think Malcolm will do this, but more for the meat with a glas of wine then for the red cells. Link to comment Share on other sites More sharing options...
Rh-fan Posted May 17, 2012 Share Posted May 17, 2012 with out the transfusion, a cold auto absorption would be nice but now you have to perform an allo-absorption.Is the patient bloodgroup A? And if yes, is anti H or IH a possibility? Link to comment Share on other sites More sharing options...
MAGNUM Posted May 17, 2012 Share Posted May 17, 2012 I do believe it could be relaxing to collect your own rabbit cells, then a hearty dinner, yum. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 17, 2012 Share Posted May 17, 2012 (edited) I think Malcolm will do this, but more for the meat with a glas of wine then for the red cells.Strangely, for someone who is virtually a carnivore, rabbit meat is not to my taste - but the glass of wine - now your talking!!!!!!!!!!!!!!! Edited May 17, 2012 by Malcolm Needs STILL can't spell!!!!!!!!!!!!!! Link to comment Share on other sites More sharing options...
Mabel Adams Posted May 18, 2012 Share Posted May 18, 2012 you're Couldn't resist, Malcolm. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted May 18, 2012 Share Posted May 18, 2012 you're Couldn't resist, Malcolm.As I've often said on this site, speling iz knot my strong point!!!!!!!!!!!!!!!!!!!!! Link to comment Share on other sites More sharing options...
Mabel Adams Posted May 19, 2012 Share Posted May 19, 2012 If the spelling of "your" and "you're" were a blood bank process we would redesign it because it is too prone to human error. Link to comment Share on other sites More sharing options...
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