emadib Posted January 1, 2009 Share Posted January 1, 2009 Can anybody tell me about the history,state of art of NAT and its application in blood banks.As well, what are the companies which provide the NAT testing products in the market.Thank you Link to comment Share on other sites More sharing options...
emadib Posted January 3, 2009 Author Share Posted January 3, 2009 (edited) No responses in 3 days...Anyway, I started to get some informatuin through continuous search...Multiplex NAT for HBV, HCV and HIV.Your help and comments are welcomed. Edited January 3, 2009 by emadib explaining progress Link to comment Share on other sites More sharing options...
emadib Posted January 3, 2009 Author Share Posted January 3, 2009 This is my first post and no one of moderators welcomed me !!!! Link to comment Share on other sites More sharing options...
emadib Posted January 3, 2009 Author Share Posted January 3, 2009 Ggggggrrrroooooommm Link to comment Share on other sites More sharing options...
Cliff Posted January 4, 2009 Share Posted January 4, 2009 This is my first post and no one of moderators welcomed me !!!!emadib,Welcome to BBT.This is not the introductions forum, we have a separate section for that so the forums don't get cluttered. See here.As for your question, my suggestion would be to review the FDA's site for USA related information. Their site is located here. Link to comment Share on other sites More sharing options...
emadib Posted January 4, 2009 Author Share Posted January 4, 2009 emadib,Welcome to BBT.This is not the introductions forum, we have a separate section for that so the forums don't get cluttered. See here.As for your question, my suggestion would be to review the FDA's site for USA related information. Their site is located here.Thank you CliffI have some questions regarding CT ratioCan you help give me a link to FAQs regarding this issue in any of this website forums or elsewhere? Link to comment Share on other sites More sharing options...
PHYLLIS Posted January 7, 2009 Share Posted January 7, 2009 You can contact the National Testing Lab. in Philadelphia (ARC) 215-451-4675Phyllis Link to comment Share on other sites More sharing options...
Mabel Adams Posted January 13, 2009 Share Posted January 13, 2009 CT ratio is just the number of units of blood doctors order crossmatched divided by the number of those units that get transfused. The AABB Technical Manual probably gives a description, but there really isn't that much to it. Interpreting the results depends on the specialty of the doc or facility and your patient population, but most hospitals try to keep the CT ratio below 2. Link to comment Share on other sites More sharing options...
emadib Posted January 13, 2009 Author Share Posted January 13, 2009 (edited) Thanks Mabel,i need some details regarding ct ratio calculation and its usein case of no units crossmatched we have a zero valuein case many units crossmached with non of them transfused we have "infinity" value regardless of how many units crossmatcheda little bit confusingcan any body give a link for a page or document that cover the ct ratio issue thoroughly? Edited January 13, 2009 by emadib Link to comment Share on other sites More sharing options...
tbostock Posted January 13, 2009 Share Posted January 13, 2009 Ideally, as stated above, you want your C/T ratio to be less than 2. Anything higher points to inefficiency (you are crossmatching too many units that are never transfused...so wasted tech time, etc). A C/T ratio of 1 would be ideal, meaning that each unit that you crossmatch is used. You really shouldn't ever have a C/T ratio of zero; if you are never transfusing any units that you crossmatch, then why are you doing the work?We don't crossmatch a lot here until we have an order from the doc to transfuse, or we have a patient with a very low hemoglobin, or they are going for a high risk surgery, such as a AAA repair. Otherwise, we wait until they want it and do a quick immediate spin crossmatch. Of course if a patient has antibodies, we do crossmatch those because we can't just do immediate spin. Link to comment Share on other sites More sharing options...
Mabel Adams Posted January 14, 2009 Share Posted January 14, 2009 If you get zero because you transfused units but you never crossmatched them, you would be violating normal BB rules in the US. Even blood given uncrossmatched is crossmatched after the fact. Thus, you could mathematically get a result of zero, but not logically. It is not mathematically meaningful to divide by zero so if you never transfuse any that you crossmatch you should get an invalid answer, not infinity. Math aside, if either of these is your situation then you have circumstances that do not require statistics to evaluate and understand what is going on. Just think about what it means if you are crossmatching a lot of units and none are transfused. I guess I would be asking "why?" not what the CT ratio is. Link to comment Share on other sites More sharing options...
manojpm Posted January 14, 2009 Share Posted January 14, 2009 Dear emadib,As per my knowledge NAT is available from Hemogenomics and Roche Diagnostics. Link to comment Share on other sites More sharing options...
NedB Posted January 18, 2009 Share Posted January 18, 2009 emadibYou calculate the C/T ratio from totals, not for each transaction. The C/T ratio is well known to nurse managers, so it is part of most hospitals QA program. For your blood bank it is important, but he numbers from which it is derived are even more important. The total number of crossmatches reflects your workload for the month. The totals number of units transfused reflects your bill from your supplier. if you are setting up a QA surveillance, you may want to also track the total number of plasma and platelets transfused, the number of units re-typed, and the number of transfusion reactions. These are the essentials. Good luck; and belatedly, welcome. Link to comment Share on other sites More sharing options...
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