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Procedure for crossmatching patients with anti-Bg?

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What is your facility's procedure for crossmatching patients with a history of anti-Bg?  For example, do you use gel crossmatch or another method? 


Our location doesn't have antisera for antigen typing.

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We do an AHG crossmatch (either by Echo or gel) only when the current antibody screen is positive. If the patient has a negative antibody screen, even if there's history of anti-Bg, we do an electronic crossmatch.

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Quite right Pat Hodges.


Anti-Bg is not clinically significant, and so does not disqualify the patient from having electronic issue.  If you don't have electronic issue Mosaics, you can cross-match by any serological technique.  Most donors do not express high amounts of Bg on their red cells, so I would suggest that you cross-match a couple of units more than the patient requires, just in case you get an incompatible unit.  DO NOT transfuse any incompatible units though.  It may be that the patient also has an antibody directed against a low prevalence antigen, and it could be that the unit's red cells express this low prevalence antigen, and then there could be a transfusion reaction.  PLAY IT SAFE!

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