Cliff Posted December 27, 2023 Share Posted December 27, 2023 Let's start 2024 with a fun challenge! We will send an email to all members today letting them know. Let's see if we can get 100 posts in one day in January. We'll start with next Thursday, January 4, 2024. We'd have over eight thousand posts if every active member made just one post! Don't save up; please post between now and next Thursday. Need some ideas? Reply to something in the unanswered topics list. If it's your first post, make an introduction. Start a new topic with something you've been curious about. Malcolm Needs 1 Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 1 Share Posted January 1 Here's one to start. This is a schematic of a molecule carrying a particular blood group antigen. The antigen is expressed on fewer Japanese individuals than most (but not all) ethnicities. What is the antigen? Link to comment Share on other sites More sharing options...
Melanie Oliveira Posted January 3 Share Posted January 3 I'm going to go with Lewis antigen??? Link to comment Share on other sites More sharing options...
Antibodiesrock Posted January 3 Share Posted January 3 I would say the H antigen Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 50 minutes ago, Melanie Oliveira said: I'm going to go with Lewis antigen??? No, I'm afraid not. Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 5 minutes ago, Antibodiesrock said: I would say the H antigen No, I am afraid not. Link to comment Share on other sites More sharing options...
donellda Posted January 3 Share Posted January 3 I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought) Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 1 hour ago, donellda said: I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought) No, I'm afraid not. Link to comment Share on other sites More sharing options...
MGM Posted January 3 Share Posted January 3 Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out. Kidd would be lacking proteins for Kidd null. Just a guess. Link to comment Share on other sites More sharing options...
Antibodiesrock Posted January 3 Share Posted January 3 Another try… Jr(a) Malcolm Needs 1 Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 (edited) 18 hours ago, Antibodiesrock said: Another try… Jr(a) Yep! See Reid ME, Lomas-Francis C, Olsson ML. The Blood Group Antigen FactsBook. 3rd edn, 2012, Academic Press. ISBN: 978-0-12-415849-8. Edited January 4 by Malcolm Needs Antibodiesrock 1 Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 Okay then, here is another one. A schematic of the showing the extracellular domain of the Piezo1 protein between amino acid residues 2198 and 2431. WHat is the Blood Group System? Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 3 Share Posted January 3 1 hour ago, MGM said: Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out. Kidd would be lacking proteins for Kidd null. Just a guess. I'm afraid not. Many of the Blood Group Systems are multi-pass proteins. Link to comment Share on other sites More sharing options...
Antibodiesrock Posted January 4 Share Posted January 4 I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system Malcolm Needs 1 Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 4 Share Posted January 4 7 hours ago, Antibodiesrock said: I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system Absolutely spot on. Well done! See Karamatic Crew V, Tilley LA, Satchwell TJ, Al Subhi SA, Jones B, Spring FA, Walser PJ, Martins Freire C, Murciano N, Giustina Rotordam M, Woestmann SJ, Hamed M, Alradwan R, Al Khrousey M, Skidmore I, Lewis S, Hussain S, Jackson J, Latham T, Kilby MD, Lester W, Becker N, Rapedius M, Toye AT, Thornton NM. Missense mutations in PIEZO1, encoding the Piezo 1 mechanosensory protein, define the Er red blood cell antigens. Downloaded from http://ashpublications.org/blood/article-pdf/doi/10.1182/blood.2022016504/1922096/blood.2022016504.pdf on 30th September 2022. Antibodiesrock 1 Link to comment Share on other sites More sharing options...
Malcolm Needs ☆ Posted January 4 Share Posted January 4 Who is this lady, and why did she win fame with regard to the genetics of the Rh Blood Group System? Link to comment Share on other sites More sharing options...
Cliff Posted January 5 Author Share Posted January 5 We did pretty well yesterday, with 28 total posts. Malcolm Needs and John C. Staley 2 Link to comment Share on other sites More sharing options...
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