Posted December 27, 20231 yr comment_87455 Let's start 2024 with a fun challenge! We will send an email to all members today letting them know. Let's see if we can get 100 posts in one day in January. We'll start with next Thursday, January 4, 2024. We'd have over eight thousand posts if every active member made just one post! Don't save up; please post between now and next Thursday. Need some ideas? Reply to something in the unanswered topics list. If it's your first post, make an introduction. Start a new topic with something you've been curious about.
January 1, 20241 yr comment_87482 Here's one to start. This is a schematic of a molecule carrying a particular blood group antigen. The antigen is expressed on fewer Japanese individuals than most (but not all) ethnicities. What is the antigen?
January 3, 20241 yr comment_87515 50 minutes ago, Melanie Oliveira said: I'm going to go with Lewis antigen??? No, I'm afraid not.
January 3, 20241 yr comment_87516 5 minutes ago, Antibodiesrock said: I would say the H antigen No, I am afraid not.
January 3, 20241 yr comment_87517 I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought)
January 3, 20241 yr comment_87518 1 hour ago, donellda said: I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought) No, I'm afraid not.
January 3, 20241 yr comment_87519 Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out. Kidd would be lacking proteins for Kidd null. Just a guess.
January 3, 20241 yr comment_87521 18 hours ago, Antibodiesrock said: Another try… Jr(a) Yep! See Reid ME, Lomas-Francis C, Olsson ML. The Blood Group Antigen FactsBook. 3rd edn, 2012, Academic Press. ISBN: 978-0-12-415849-8. Edited January 4, 20241 yr by Malcolm Needs
January 3, 20241 yr comment_87522 Okay then, here is another one. A schematic of the showing the extracellular domain of the Piezo1 protein between amino acid residues 2198 and 2431. WHat is the Blood Group System?
January 3, 20241 yr comment_87523 1 hour ago, MGM said: Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out. Kidd would be lacking proteins for Kidd null. Just a guess. I'm afraid not. Many of the Blood Group Systems are multi-pass proteins.
January 4, 20241 yr comment_87525 I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system
January 4, 20241 yr comment_87526 7 hours ago, Antibodiesrock said: I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system Absolutely spot on. Well done! See Karamatic Crew V, Tilley LA, Satchwell TJ, Al Subhi SA, Jones B, Spring FA, Walser PJ, Martins Freire C, Murciano N, Giustina Rotordam M, Woestmann SJ, Hamed M, Alradwan R, Al Khrousey M, Skidmore I, Lewis S, Hussain S, Jackson J, Latham T, Kilby MD, Lester W, Becker N, Rapedius M, Toye AT, Thornton NM. Missense mutations in PIEZO1, encoding the Piezo 1 mechanosensory protein, define the Er red blood cell antigens. Downloaded from http://ashpublications.org/blood/article-pdf/doi/10.1182/blood.2022016504/1922096/blood.2022016504.pdf on 30th September 2022.
January 4, 20241 yr comment_87529 Who is this lady, and why did she win fame with regard to the genetics of the Rh Blood Group System?
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