Jump to content

Featured Replies

Posted
comment_87455

Let's start 2024 with a fun challenge!

We will send an email to all members today letting them know.

Let's see if we can get 100 posts in one day in January.

We'll start with next Thursday, January 4, 2024.

We'd have over eight thousand posts if every active member made just one post!

Don't save up; please post between now and next Thursday.  :)

Need some ideas?

  • Reply to something in the unanswered topics list.
  • If it's your first post, make an introduction.
  • Start a new topic with something you've been curious about.
  • Replies 16
  • Views 2.4k
  • Created
  • Last Reply

Top Posters In This Topic

Most Popular Posts

  • We did pretty well yesterday, with 28 total posts.   

  • Antibodiesrock
    Antibodiesrock

    Another try… Jr(a) 

  • Malcolm Needs
    Malcolm Needs

    Yep!  See Reid ME, Lomas-Francis C, Olsson ML.  The Blood Group Antigen FactsBook.  3rd edn, 2012, Academic Press.  ISBN: 978-0-12-415849-8.

Posted Images

comment_87482

image.png.4f32ee022943d9702a1d83aa341e3f22.png

Here's one to start.  This is a schematic of a molecule carrying a particular blood group antigen.  The antigen is expressed on fewer Japanese individuals than most (but not all) ethnicities.  What is the antigen?

comment_87515
50 minutes ago, Melanie Oliveira said:

I'm going to go with Lewis antigen???  

No, I'm afraid not.

comment_87516
5 minutes ago, Antibodiesrock said:

I would say the H antigen :fingerscrossed:

No, I am afraid not.

comment_87517

I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought)

comment_87518
1 hour ago, donellda said:

I think it's Diego but I have been retired for a few years now and my mind is rusty (although this was my first thought)

No, I'm afraid not.

comment_87519

Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out.  Kidd would be lacking proteins for Kidd null.   Just a guess.  

comment_87521
18 hours ago, Antibodiesrock said:

Another try… Jr(a) 

Yep!  See Reid ME, Lomas-Francis C, Olsson ML.  The Blood Group Antigen FactsBook.  3rd edn, 2012, Academic Press.  ISBN: 978-0-12-415849-8.

Edited by Malcolm Needs

comment_87522

Okay then, here is another one.

A schematic of the showing the extracellular domain of the Piezo1 protein between amino acid residues 2198 and 2431.

WHat is the Blood Group System?

image.png.088fcd39e01862e7ccb9a996ec2435eb.png

comment_87523
1 hour ago, MGM said:

Well, its a multi-pass protein blood group so could be RH; Diego, Lewis ruled out.  Kidd would be lacking proteins for Kidd null.   Just a guess.  

I'm afraid not.  Many of the Blood Group Systems are multi-pass proteins.

comment_87525

I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system :confused:

comment_87526
7 hours ago, Antibodiesrock said:

I heard a lecture a while back, and I can’t find my notes, but I believe this could be the Er blood group system :confused:

Absolutely spot on.  Well done!

See Karamatic Crew V, Tilley LA, Satchwell TJ, Al Subhi SA, Jones B, Spring FA, Walser PJ, Martins Freire C, Murciano N, Giustina Rotordam M, Woestmann SJ, Hamed M, Alradwan R, Al Khrousey M, Skidmore I, Lewis S, Hussain S, Jackson J, Latham T, Kilby MD, Lester W, Becker N, Rapedius M, Toye AT, Thornton NM.  Missense mutations in PIEZO1, encoding the Piezo 1 mechanosensory protein, define the Er red blood cell antigens.  Downloaded from http://ashpublications.org/blood/article-pdf/doi/10.1182/blood.2022016504/1922096/blood.2022016504.pdf on 30th September 2022.

 

comment_87529

large.DSC_0057.JPG.fb87f20007b7d991c0f228c729539afd.JPG

Who is this lady, and why did she win fame with regard to the genetics of the Rh Blood Group System?

  • Author
comment_87563

We did pretty well yesterday, with 28 total posts.  :) 

Create an account or sign in to comment

Recently Browsing 0

  • No registered users viewing this page.

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.