I recently had a patient with reactions almost like Davids. Just curious what others think of it. I sent it out to an IRL. But the patient had a negative ABSC with a previous sample was transfused 2 units and now is positive. Looks like mixed field in gel (the top layer on the gel seemed a little to thick to be fibrin), gel panel looked the same but the auto control was 1+ (no top layer), 2 of the 11 cell panel looked negative (with maybe fibrin on the top), and 1 of 11 looked like a good 4+ (really no cells on the bottom). So I was thinking an IgM/cold antibody. DAT- IgG negative, C3d positive (Pre transfusion DAT was negative). LISS tube method was negative at all phases. Cold Screen only the I negative cell reacted 4+ at IS, RT,15C and 4C, the AC was 3+ at 15C and 4C and Screening cells were 1+wk at 15C adn 4C. Any thoughts?