August 19, 1994
MEASURING HEMOGLOBIN CONCENTRATION AFTER TRANSFUSION.
AS Brett reviewing Wiesen AR et al. Ann Intern Med 1994 Aug 15.
At what point after blood transfusion is it possible to get a reliable measure of the increase in hemoglobin concentration? These researchers tackled this question by measuring hemoglobin concentrations in 39 patients 15 minutes, 1 hour, 2 hours, and 24 hours after the patients received two units of packed red cells. None of the patients had active or recent bleeding.
The mean baseline hemoglobin level was 7.4 g/dl. Fifteen minutes after the transfusion, the mean hemoglobin concentration was 9.4 g/dl, and remained at this level throughout the first 24 hours. Various clinical variables such as body size, recent diuretic use, or duration of transfusion did not influence these results.
AS Brett
Comment
Determination of hemoglobin concentration 15 minutes after transfusion of packed cells accurately reflects the steady-state concentration for the next 24 hours. When a measure of the effect of a transfusion is needed, a single hemoglobin determination shortly afterward is sufficient.
Citation(s):
Wiesen AR et al. Equilibration of hemoglobin concentration after transfusion in medical inpatients not actively bleeding. Ann Intern Med 1994 Aug 15 121 278 280
PubMed abstract (Free)Web of Science
- See more at: http://www.jwatch.org/jw199408190000005/1994/08/19/measuring-hemoglobin-concentration-after#sthash.YLIdWCz2.dpuf