We've sent tens of thousands of units through our pneumatic tube system. We have numbered/designated, padded/insulated containers for blood products. To request blood be released from our department we have a paper form with patient identifiers and product needed. We use this to match the patient info to the crossmatch/assignment card and to the patient's info in the computer system. We document a few details relating to the blood issuance in the computer and on the form. We keep a copy of the form in the blood bank, send a copy with the blood product, and set a blood bank timer for 15". (I hear some newer tube systems have integrated delivery receipt/timers/whatnot - ours doesn't) The RN checks that the blood received is for their patient and shoot us the form/pneumatic tube back to us as confirmation of receipt. If the timer goes off before we get the form/tube back, we call and annoy them until they comply (and to confirm they receive the blood, of course). We only send blood to certain locations and only send red cells/ plasma. We don't send blood for a patient with any special transfusion requirement (e.g. antigen-negative, irradiated, etc.) anything that would be difficult, costly, or time consuming to replace. Good luck! There's plenty of info out there to help you validate the process.