[LOT TO LOT ON FMS]

We run the old controls w the new kit reagents (anti-D, indicator cells and controls).   The controls should react as anticipated.

[Emergency Release]

I think that your institution may develop whatever means they feel appropriate for emergency release.  The only caveat I have is that the MD who is  ordering is documented on the request.  Many times computer generated orders only have the attending who is in the system.  Definitely keep the phone call.

[Temperature log tag]

On ‎06‎/‎08‎/‎2020 at 12:12 PM, NLiveris said:

Digi-Trax offers a 10 degree temperature indicator that our customers say is accurate, easy to use and reliable. For more information or free samples, visit: https://bit.ly/2BMtmyv or call 800-356-6126

I've played with these but never got around to validating them.

[FDA Registered for Verax testing]

I would say no.  You are not manufacturing or modifying a product. 

[Temperature log tag]

I like HemoTemp II.  They display a current internal temp and have a blue indicator (flower) which irreversibly turns black if the unit has gotten warmer than 10C.  Easy to attach; easy to validate.

[Brain Cramp]

Thanks - that's what I thought but could only find info on crises.

[Brain Cramp]

Hi All

Having a brain cramp or just getting old:  patients w sickle cell disease.  Do they always get Hgb S neg rbcs or only in crisis?  Can't find an answer in the books.

Thanks ahead of time.

[EDTA Specimen]

thanks

[EDTA Specimen]

Thanks.

[EDTA Specimen]

Does anyone accept EDTA tubes which are less than half filled?

Why or why not?  Thanks in advance.

[good manufacturing practice- Irradiating in house]

Not only that but you also need to be FDA registered (when you produce a new blood product).

[Convalescent Plasma]

We are building a separate product

[Convalescent Plasma]

On ‎04‎/‎13‎/‎2020 at 1:40 PM, AMcCord said:

 

Epic Guidelines - Prepare and Transfuse Convalescent Plasma for COVID.docx 16.74 kB · 81 downloads

I am unable to access this link.  It goes nowhere for me.

[Positive Antibody screen but negative antibody ID panel]

47 minutes ago, Baby Banker said:

This is a long shot, but if your patient is black and transfused often, it could be ant-Jsa or anti-V/VS.  We see that not infrequently with our sickle cell patients who are on a chronic transfusion protocol. 

It is a long shot.  I don't think I've ever seen a Jsa+ screening cell.

Plus - it would be nice to know how strong the reaction(s) was and which cell(s) was reacting.

[Day 4 and 5 Bacterial Testing- Verax (PGD)]

I have a hard time implementing something I may have to use 2-3x/year.  Hard to maintain competencies for something like this, esp with an all generalist staff.

[Novel Corona Virus]

Has anyone seen anything documented about this virus stripping Heme iron. leaving rbcs unable to transport O2?

Saw a blurb w no references. 

[Day 4 and 5 Bacterial Testing- Verax (PGD)]

My lab is going to try and go with all pathogen reduced plts.

[Uncertainty of Measurement in Transfusion Services]

ABORhs aren't measurements - are they?  I agree w Malcolm.  Though, I don't know how you would do the calculation for titers (I guess you quantitate Ab levels too (anti-D).  I also think I've seen questions and comments on this topic here in the past.

[Blood Supplier Delivery and Shipping Boxes]

interesting.  First I've heard of charging for the boxes.

[Validation studies]

Run some panel cells;  negative, heterozygous and homozygous.

[Blood Bank usage by Covid19 Patients]

Wish I could offer you some experience w these patients.  Currently we've only had one positive pt and that individual was not admitted.   We don't anticipate component usage for these folks but you never know.

[serofuge]

4 hours ago, bldbnkr said:

I second this question - my trusty old Clay Adams just died and was deemed unrepairable.  Does anyone have a favorite since I have to purchase a brand new blood bank serofuge?

Drucker says they used to make those for CA.  Their serofuge has a different body but the same rotor and guts.  FYI.

[HX of WAA Case]

On ‎03‎/‎10‎/‎2020 at 8:49 PM, Bbank90 said:

Taking this case further...an alloadsorption was done, only one cell was positive when redoing the screen. C and E were then ruled out with a select cell. 
 

If you have done the alloabsorption, do you not elute and test the absorbed abs?  I find it hard to believe that a patient would be sensitized to all the ags except C and E.  (The most abs I've ever encountered were 10).

[Vision Antigen Typing & Meditech]

That's up to you and your Medical Director.  One thing to consider - that would be a lab developed test.  I thought I read a few years ago that the FDA was going to look at those (LDTs) - I think there was going to be a $250,000.00 fee (the initial fee for them to evaluate proposed new tests/drugs).  Also, when the Orthos and Immucors validate their antisera I believe they run considerably more than the "20" samples (including variants), so, while you may validate your process I don't believe your validation is as extensive, esp since you will be using reagent "off label".   I'd be more concerned with the LDT.  I'd check w the FDA to see their take on your proposal.  

FYI - I've used gel off label for years w antigen typing (and a few other assorted tests).

[The COVID-19 challenge]

That's the truth John.  Us small places are at the mercy of the blood suppliers.