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The 5 or 7 day shelf life of PR or LVDS platelets depends on the timing and method of how the bacterial sampling is being done. There were several options laid out by the FDA when the whole LVDS thing was implemented, and ARC chose to go with the 36 hour LVDS process, which did not allow for a 7 day platelet expiration, but only a 5 day. Other blood suppliers chose to perform LVDS at 48 hours, which will give you a 7 day expiration. It is an ARC problem. Verax is not FDA approved for PR platelets, so you can't use it to extend the expiration. We were doing Verax on our normal PAS platelets before the LVDS rule went into effect, and had to stop once ARC switched over to all PR. We recently brought in cold stored platelets from ARC. FDA says these are best for bleeding patients, but won't allow transfusion services to maintain a dual inventory and preferentially select CSPs over RT platelets based on the patient need. They say if all you have is CSPs, then they can be given to anyone who needs platelets. ARC supplies us from Omaha and St. Paul, and I am in Denver, so getting RT platelets here is feasible, and has been fine, but it's not practical as we have to get a shipment daily to maintain our inventory and keep platelets in house for trauma (Level 1 adult, level 2 peds center). We decreased our standing order of RT platelets to get CSPs in house, and we use the CSPs only when we are out of RT platelets - as the FDA has said is approved, but also to reduce the amount of platelets we are tossing due to short expiration.

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Thank you Mabel. That's exactly what I've been looking for.

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former management was a huge proponent of OVERKILL - so we have: REES system for doors and internal temps (temps are compared weekly to "manual" temps to assure all are within acceptable range) Document temp of "built in" digital readout daily (High and low alarm checks quarterly) have separate, digital thermometer probes measuring top and bottom temps, documented daily calibrated annually AND, last but not least, a global tracker that shows temp and stores info so if there's any question, the logged info can be downloaded and printed. calibrated annually no one will ever be able to say we weren't tracking our temps!

Diego Blood Group System Diego Blood Group System This question was submitted by forum member, Malcolm Needs. Any errors are those of the site admin, not Malcolm. Submitter Cliff Category BloodBankTalk Submitted 05/09/2024  

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We keep single cryo units for neonates. We thaw it and pull it into a filter syringe, so it is filtered when we issue it like everything else that we issue to NICU. We have been negotiating the proper dosage after an order for 15 ml/kg on a term newborn seemed excessive and required 2 single cryo units. We came upon a guide from Children's of Minnesota that our neonatologists like. Cryoprecipitate Transfusion Dosing Table (childrensmn.org)

We put two sensors in our big refrigerators but only test alarms on the top one. The bottom one just records the temperature. It would alert us if it got out of range but isn't the one we depend on.

I'm correcting this because I learned that Diluent 2 does have antibiotics, but it lacks some other chemicals used in prediluted cells. This information is from the instructions for use so you can verify what is in each.

Found this conclusion statement online from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11016247/ Chemical and Microbiological Changes of Expired Platelet Concentrate Chemical and Microbiological Changes of Expired Platelet Concentrate Nora Y Hakami, 1 Abdulrahman M Al-Ahdal, 1 , 2 Afnan J Al-Sulami, 3 Httan M Alabbadi, 3 Mamdouh M Sindi, 4 Kholoud A Gholam, 3 Maiman M Bayuomi, 3 and Talal Qadah 1 Author information Article notes Copyright and License information PMC Disclaimer "Platelet concentrate, among other blood components, is considered an inventory management challenge due to its short shelf life. This study showed that extending platelet concentrate storage is possible for up to seven days without any chemical or microbial changes. Extending storage time for platelet concentrate will save money, increase availability, and save more patients. Further studies are required to evaluate platelet function during expiry time and to assess the stability of platelet morphology and function. It is recommended that platelet concentrate storage time be extended to day seven after obtaining approval from the medical director in case of shortages or high demands. However, further studies must confirm these findings and determine the most effective strategies for improving platelet concentrate quality. Additionally, it would be ideal to investigate the clinical implications of these findings."

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Hello Heather J., Welcome to PathLabTalk. Please feel free to browse around and get to know the others. If you have any questions, please don't hesitate to ask. Heather J. joined on the 05/08/2024. View Member

Hello-my lab plans to implement remote temperature monitoring devices throughout each department. My question pertains to double door refrigerators: would I need two sensors (a high and a low) or just one sensor in the middle of the refrigerator to be compliant with inspections? Any advice is greatly appreciated!

Welcome to PathLabTalk.com! Please consider signing up for one or more of our newsletters. PathLabTalk is on Twitter; follow us at @pathlabtalk. https://twitter.com/pathlabtalk. PathLabTalk is on Facebook. Also, please consider supporting PathLabTalk by visiting our store.

Hello HMB, Welcome to PathLabTalk. Please feel free to browse around and get to know the others. If you have any questions, please don't hesitate to ask. HMB joined on the 05/08/2024. View Member

Latest issue of AABB News mentions that both LVDS and PR platelets have seven-day shelf-lives but ours from ARC are still 5. Can someone explain how we can get 7-day PR platelets? Is this an ARC problem? We really don't want to start using Verax on LVDS platelets because we hope that more improvements are coming to platelet dating soon. Cold stored can be used only for bleeding patients so we couldn't always use them up, they must be on standing order only, and we are 4 hours' drive from our supplier for getting more RT plts.

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