Antigen Index Chart

[SMILLER]

Does someone know of a link to a one or two-page Antigen Chart?  You know, one that lists antigens, thier reaction characteristics, and how common they are? 

 

We have a big chart, but it would be nice to have a smaller one that we can stick up in our student cubby, so when we ask inpertinent questions like "how many units are you going to have to screen in order to get two compatable...", they can do the math.

 

Thanks Scott

[Auntie-D]

Ooo I can help with that! I'll dig mine out and attach it later

[Auntie-D]

Found it!

Antigen_specificity_and_blood_selection1.docx

[SMILLER]

Awesome!  That looks pretty good!  Thanks alot!

 

Scott

[Eagle Eye]

Found it!

Anti-f may mimic Anti D+C with C showing higher dosage – can cause DHTR and HDN

 

Please check the note at bottom..........Isn't anti-f is combination of anti-c+e? 

[Malcolm Needs ☆]

You are perfectly correct in one way Eagle Eye, except that anti-f is not a combination of anti-c+e, but a compound anti-ce - in other words, it will react with a ce antigen on the same haplotype (such as dce or Dce), i.e. when, for want of a better way of putting it, the RHc and RHe genes are in the cis position, but will not react with red cells when the c and e antigens are derived from different haplotypes (such as DCe/DcE), i.e. when, for want of a better way of putting it, the RHc and RHe genes are in the trans position.

 

All that having been said, however,it is a typographical error anyway, as it should read, "anti-G may mimic anti-C+D, with the anti-C normally showing stronger reactions than the anti-D."

 

Unfortunately, although citing an NHSBT Document at the bottom (SPN/DDR/RC/020/02), this is not from the actual document (which is 33 pages in length, which has just been updated by the author - Dr. Geoff Daniels on 12 January 2015 - and which does not contain this table).

[Auntie-D]

You are both right - it was a typo sorry

 

Double typo

 

I had added it after a patient had a DHTR due to anti-f in flying squad units.

Edited February 12, 2015 by Auntie-D

[Dr. Pepper]

Auntie, that's a nice chart. One question: at the bottom of the red Antibody column on the left, below anti-Lub, there's an entry "Active @37^oC" What is this refering to? Undetermined antibodies to low incidence antigens?

 

Thanks - Phil

[Auntie-D]

Auntie, that's a nice chart. One question: at the bottom of the red Antibody column on the left, below anti-Lub, there's an entry "Active @37^oC" What is this refering to? Undetermined antibodies to low incidence antigens?

 

Thanks - Phil

 

Yup, but there wasn't enough room

[Moncada]

Also curious about the frequency column, assuming this is the freq. of compatilbe units, I think k(cellano) and Kpb frequencies are in error. The frequency listed for these 2 antibodies reflects the "incompatible" rates.