Acute Transfusion Reaction

[RichU]

Why are haemolytic reactions excluded from definition of ATR?

SHOT in UK only defines Febrile, Allergic and Hypotensive

Cheers 

[Malcolm Needs ☆]

I think your best bet to get an accurate answer to this question is to ask them (on line, and then publish their answer here).

[Neil Blumberg]

Makes no sense to me if that's true.  Hemolytic reactions have always been in a special category because they were the most common cause of acute life threatening signs and symptoms.  Perhaps that's why. 

Then again, most professional societies and hematology/transfusion medicine textbooks/reviews completely ignore the most common serious post-transfusion toxicities. This is perhaps because there is an expert opinion (dogma) driven belief that thrombosis, infection and inflammation, sepsis and organ failure occurring more than 4-6 hours after transfusion could not possibly be due to transfusion.  Wrong, but a deeply held belief based upon decades old methodologically fatally flawed meta-analyses of randomized trials which told people what they hoped was true :).

Edited Monday at 05:59 PM by Neil Blumberg

[RichU]

@Malcolm Needs, I have done as you suggested and await a reply.

Rich

[RichU]

Serious Hazards Of Transfusion (SHOT) have haemolytic transfusion reactions in separate reporting categories.

All of the following can be 'Serious Adverse Reactions';

HTR Acute

HTR Delayed

HTR Hyperhaemolysis

FAHR

 

See SHOT definitions if you want more info.

SHOT Definitions - Serious Hazards of Transfusion