Posted March 7Mar 7 comment_93112 Why are haemolytic reactions excluded from definition of ATR? SHOT in UK only defines Febrile, Allergic and Hypotensive Cheers
March 7Mar 7 comment_93120 I think your best bet to get an accurate answer to this question is to ask them (on line, and then publish their answer here).
March 10Mar 10 comment_93145 Makes no sense to me if that's true. Hemolytic reactions have always been in a special category because they were the most common cause of acute life threatening signs and symptoms. Perhaps that's why. Then again, most professional societies and hematology/transfusion medicine textbooks/reviews completely ignore the most common serious post-transfusion toxicities. This is perhaps because there is an expert opinion (dogma) driven belief that thrombosis, infection and inflammation, sepsis and organ failure occurring more than 4-6 hours after transfusion could not possibly be due to transfusion. Wrong, but a deeply held belief based upon decades old methodologically fatally flawed meta-analyses of randomized trials which told people what they hoped was true :). Edited March 10Mar 10 by Neil Blumberg
March 11Mar 11 Author comment_93169 @Malcolm Needs, I have done as you suggested and await a reply. Rich
March 12Mar 12 Author comment_93185 Serious Hazards Of Transfusion (SHOT) have haemolytic transfusion reactions in separate reporting categories. All of the following can be 'Serious Adverse Reactions'; HTR Acute HTR Delayed HTR Hyperhaemolysis FAHR See SHOT definitions if you want more info. SHOT Definitions - Serious Hazards of Transfusion
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