This is the criteria we've established for the product
Criteria for thawed plasma transfusion includes:
è -PT and PTT >1.5 x the mean normal value in a non-bleeding patient scheduled for surgery or invasive procedure;
è -Diffuse microvascular bleeding, transfusion of >1 blood volume, and PT and PTT >1.5 x the mean normal value or not yet available; and
è -warfarin overdose with major bleeding or impending surgery.
Other indications may include:
è emergency reversal of warfarin,
è treatment of plasma anticoagulant deficiencies such as protein C, protein S, or antithrombin III when specific therapy is not available
Advisable exceptions include
è Inpatients with Factor VIII deficiencies,
è Severe DIC,
è Thrombocytopenia Purpura
è Hemolytic Uremic Syndrome.
Hope this helps
Sandy Smietana
Genesis Clinical Lab
MacNeal Hospital