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Hello Joe Territo, Welcome to PathLabTalk. Please feel free to browse around and get to know the others. If you have any questions, please don't hesitate to ask. Joe Territo joined on the 04/26/2024. View Member

This is just my opinion. First, it's usually not a titer but a single-point dilution. What dilution? It's truly arbitrary. Some go 1:50, some 1:100, others 1:200. It depends on what the facility medical director will accept. Your colleague should collaborate with their medical director to determine what they feel is "safe". This cut-off will not prevent reactions, only minimize the risk. Then from there, it should be a simple procedure of a single-point dilution, with a cut of 1+, 2+... or less.

Hi everyone, a colleague needs an SOP for the titration of hemagglutinins for LTOWB. Could you please share your SOPs? Thanks in advance for all your help.

Sad to hear this. We love our MaxQ coolers and MTP coolers and will probably have to replace the whole thing when the handles go out. Boo

I agree with Bet'naSBB - the IS XM must be done in either tube or gel/other serologic method to verify ABO compatibility. Since a patient with a current or history of clinically significant antibody does not qualify for electronic crossmatch, the serologic version must be included with the AHG phase XM.

The question was, do you have to do ISXM when the patient required full XM........ The visions can do the ISXM when they do the full XM - you just have to program it correctly - and it uses a buffer card. If you don't want to do the IS XM in a buffer card, you would have to do the ISXM in tube to verify ABO Compatibility. As stated above, The IgG card used for full XM is not "approved" to "catch" ABO compatibility. I think you have to do it - even if your BB LIS is capable of flagging an ABO incompatibility - but someone correct me if I'm wrong.

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Same here in our lab.

Is there such a product as dried red cells? This information in this question / answer was generously provided by AABB. Any errors are those of the site admin, not AABB. Mention of specific products or equipment in this AABB publication does not represent an endorsement of such products by the AABB, nor does it necessarily indicate a preference for those products over similar competitive products. Efforts are made to have publications of the AABB consistent in regard to acceptable practices. However, they may not be. As new developments in the field of relationship testing occur, changes may be recommended to the AABB Standards for Blood Banks and Transfusion Services. However, It is impossible to revise each publication when such a change is adopted. Thus, it is essential that the most recent edition of the Standards be consulted as a reference in regard to current acceptable practices. Copyright © 2018 by AABB. AABB has granted permission to republish on PathLabTalk. If you want to purchase the source material from which this was quoted, please visit here. Submitter Cliff Category BloodBankTalk Submitted 04/25/2024  

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