Anamnestic response-should we document as transfusion reaction?

[LIMPER55]

60 days after transfusion--a clinically significant antibody is identified.

Should we document with a transfusion reaction interpretaion?

Order a transfusion reaction interpretation and notify attending MD?

 

[Malcolm Needs ☆]

In a word - NO!

[tbostock]

No.

[goodchild]

Somewhat misleading title!

In the case of a delayed serological reaction identified 60 days post transfusion. We wouldn't do anything extra.

In the case of a delayed serological reaction identified <30 days post transfusion. We would document our workup, with a pathologist interpretation, but wouldn't notify the physician specifically. This is mostly for data purposes. (See CDC Hemovigilance)

In the case of a delayed reaction identified 60 days post transfusion where we identify that the patient had a previous history of the antibody we may do a little more but it would depend if we could identify that the transfused unit had an incompatible phenotype, any laboratory results from relevant time periods, and any subjective history (symptoms) from the patient.