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Glass vs. Plastic Tubes for Storage


Terry Rees

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We currently store our patient serum/plasma samples (after separation) in glass tubes.  We would like to switch to plastic for "trash" reasons.  Does anyone know of a reason why we can't?  Also, I don't want to have to do a validation.  The samples are intially tested for antibodies and are only occasionally retrieved for additional testing.   

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We currently store our patient serum/plasma samples (after separation) in glass tubes.  We would like to switch to plastic for "trash" reasons.  Does anyone know of a reason why we can't?  Also, I don't want to have to do a validation.  The samples are intially tested for antibodies and are only occasionally retrieved for additional testing.   

We do not separate plasma from the patient's original blood sample container.

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If you do decide to go over to plastic, there should be no problem, but immunoglobulins are, of course, proteins, and so you need to make sure that the plastic you choose is more of the more "modern" type that does not adsorb protein onto its surface (by electrostatic forces), otherwise any antibodies present may weaken or disappear entirely upon storage.

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