double platelet collection

[lyla_n]

whats the donor eligibility criteria for Double platelet donation.. also if we collect 5x 10(11) platelets do we split it? hw does it qualify in quality control?

[lyla_n]

wat should be the donor pre counts for Double platelet collection and also for triple platelet collection?

[David Saikin]

If you want to split a plt collection there should be at least 3.0x10(11) per bag. You will have to determine your own criteria for double/triple collections.

[ColleenA]

Precounts are helpful and the higher the count the more likely a unit is to split but it depends on what type of apheresis machine you are using. You may want to talk to the vendor to see if they have any guidance as to what pre-count is likely to split on that particular machine. Most of the newer machines have you program in the height and weight of the donor to calculate the total blood volume and then incorporate the pre-count to figure out what type of collection they are eligible for. The other variable is time. The longer a donor sits on the machine the more plts you collect and the more likely you will have split units. It depends on how nice your donors are and if they have extra time to stay on the machine. Good luck.

[Liz]

I agree with Colleeen, precounts are important, but you won't find standards as to "what pre count corresponds to what collect". Although the rough estimate may be 6 units for 150,000 and you take it from there keeping in mind that the donor should remain above 100,000 post donation. The best thing is to have the equipment calculate it for you.

"...AABB Standards requires that an apheresis platelet component contain at least 3 × 1011 platelets in 90% of sampled units. With newer technology and more efficient processes, higher yields of platelets may be obtained from one donor, and the original apheresis unit may be split into multiple units, each of which must meet minimum standards. Some instruments are programmed to calculate the yield from the donor’s hematocrit, platelet count, height, and weight. "

and

"If the donation interval is less than 4 weeks, the donor’s platelet count should be above 150,000/μL before subsequent plateletpheresis occurs."