I have discovered that too with the @ cells on the Ortho panel. Sometimes it does rule everything out with a homozygous cell, but not all the time. Here's another question. We have a special antibody for Rhogam recipients, D residual Rhogam, which is resulted out only if we have a definite date for Rhogam. With a real anti-D, we would always do a gel crossmatch. We are doing that with Rhogam as well, even though the panel is negative. Is it safe to discontinue gel crossmatches if we have negative antibody screens after that? We had a patient who was last in with Rhogam in 2005, but has had three negative screens this year. I feel it is safe to revert to an immediate spin and delete the antibody. Thanks! Mari