Presumably people will centrifuge the platelet unit, then remove some plasma, and resuspend the platelets. Is this how it`s done? I was always told this may activate the platelets and lead to a reduction in viable platelets, so this was not recommended where I used to work. Is this reasoning correct? The maternity hospital I am now at will try its best to give group-specific platelets. If they are not available, we would give other groups only if absolutely necessary - except we would NOT give group O platelets to a non-group O recipient. Whilst on this topic, would you give Rh Pos platelets to a Rh neg female baby (assuming no Rh Neg platelets are available)?