Jump to content

Validation of Volume Reduced Platelets Process


Recommended Posts

Our facility is updating our floor model centrifuge which will product volume reduced platelets (Apheresis Platelet which is Plasma Reduced). 

I'm interested if anyone has validated this process in their facility, and if so...what product parameters did you use to ensure volume reduction yielded viable platelets? 


We will be performing IQ/OQ of the centrifuge but in planning for the PQ of the product, we are initially considering:


- volume of product pre/post

- platelet count in pre/post (or lack of platelet/reduction of platelets in the 'removed' portion...) 

- visual inspection of vol reduced platelet (i.e., the swirling of platelets)


If you've recently done it, know of any good references or can share any good (or bad!) experiences, please do!  I imagine it would be similar if you've recently validated washing platelets, too...


Thanks - and happy 4th!

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Advertisement

  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.