kmmoton Posted November 13, 2013 Share Posted November 13, 2013 If a patient is classified as A2B, should their reverse A1 cells always come up positive or is it possible for the reverse A1 cells to be negative? Link to comment Share on other sites More sharing options...
SMW Posted November 13, 2013 Share Posted November 13, 2013 Only about 25% of A2B individuals will have an anti-A1 detected by routine ABO testing methods. David Saikin and Yanxia 2 Link to comment Share on other sites More sharing options...
L106 Posted November 13, 2013 Share Posted November 13, 2013 According to Peter Issitt's book Applied Blood Group Serology (paraphased): Between 1 and 8% of A2 individuals produce Anti-A1, and approximately 22 and 35% of A2B individuals produce Anti-A1. So, it is very typical to not find Anti-A1 in the plasma of A2B patients. Donna Yanxia and David Saikin 2 Link to comment Share on other sites More sharing options...
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