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Cord Blood Elutions for ABO and RhIG D


tlorme

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Can anyone tell me if they routinely perform an elution on a cord blood when you know the mom's plasma contains anti-D due to RhIg and/or there is an ABO incompatibility between mom & baby (ie: mom's group O and baby's group A)? :confused:

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We do not do an elution when the positive DAT is likely to be ABO related (O mother has an A or B baby) or due to RhiG. The treatment in those cases is the same the doctor only has to monitor the bilirubin to determine if more time under the light is needed.

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We have always done eluates on newborns with positive DATs.... a freeze-thaw when we suspect an ABO antibody, and an acid eluate when we suspect anything else. We are also looking to discontinue them. Thoughts??

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We do acid elutions on all inpatient positive neonatal DATs (<4 months old). For outpatients, we just add a canned comment that says to contact the TS if further testing is desired.

A lot of adult hospitals don't do them if it looks like ABO ab or if the maternal ab is already known. We are a children's hospital (not a delivery hospital), so we don't always get the maternal ab information and don't like to "trust" the information provided by another TS or physician.

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