yaya Posted January 23, 2006 Share Posted January 23, 2006 we are using immediate crossmatch for all with no history of antibodies but since we are using EDTA samples with tube method in immediate spin there some difficualties in reading the results ( getting false positive with heigh protien specimen ) any suggestions ? :cries: :cries: :cries: Link to comment Share on other sites More sharing options...
adiescast Posted January 23, 2006 Share Posted January 23, 2006 We use EDTA samples for all of our work. I have not noted a problem with the immediate spin crossmatch. What are you seeing? Is it Rouleaux? Link to comment Share on other sites More sharing options...
Cathy Posted January 24, 2006 Share Posted January 24, 2006 We occasionally see rouleaux. We do a saline replacement and let it go if negative. Link to comment Share on other sites More sharing options...
yaya Posted January 24, 2006 Author Share Posted January 24, 2006 we are facing this frequently and iam warried if that it is due to any problem of sample collecton !!!!!!!!!!!!!!!!!!!!!!!! Link to comment Share on other sites More sharing options...
jssa1891 Posted January 24, 2006 Share Posted January 24, 2006 We have been doing immediate spin crossmatches with EDTA samples for several years. We have seen rouleaux only very rarely. However, if the EDTA tube is not well mixed immediately following collection, you could certainly have a problem with fibrin, which would make tests difficult to read and interpret. Link to comment Share on other sites More sharing options...
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