Timeline of repeating the antibody panel for a historical patient

[JT Super]

Hi, I was wondering where in the AABB technical manual states the timeline of repeating the antibody panel for a historical patient? Is it 2 weeks, 3 weeks, or every 3 days? Which is the most common and safest practice?

[John C. Staley]

Just a thought but you may want to check the AABB Standards instead of the Technical Manual.  Your question is more of a standards question than a technical one.  Since I no longer have access to the Standards this is the best I can do.

 

[SbbPerson ☆]

On 2/7/2024 at 2:20 PM, JT Super said:

Hi, I was wondering where in the AABB technical manual states the timeline of repeating the antibody panel for a historical patient? Is it 2 weeks, 3 weeks, or every 3 days? Which is the most common and safest practice?

 

 

 

5.14.4

 

A new sample shall be obtained from the patient within 3 days prior to transfusion in the following situations:

1. If the patient has been transfused in the preceding 3 months with blood or a blood component containing allogeneic red cells.
2. If the patient has been pregnant within the preceding 3 months.
3. If the history is uncertain or unavailable. Day 0 is the day of draw.

5.14.5

 

In patients with a history of previously identified antibodies, testing shall be capable of detecting and identifying the presence of newly formed clinically significant antibodies. Standard 5.14.3.1 applies.

 

5.14.3.1

When antibodies are detected, additional testing shall be performed to identify antibodies of clinical significance.

 

Source: AABB Standards for Blood Banks and Transfusion Services, 33rd Edition, effective April 1, 2022 (Published: 12/21/2023 )