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Method to Method Comparison

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  • 4 months later...

Hi David,

I am struggling with a method to method comparison for apheresis platelet counts.  Please see below.  I wrote this for my data eval and determination of acceptance.

● An acceptable bias or allowable total error of ±7.0% for platelet count was set for this method to method comparison.  The mean of the Abbott Cell-Dyn method is 1.5408 with a standard deviation of 0.2248.  It is 95% confident that the sample mean falls between 1.47199 and 1.60961 or ±4.5%. 

The mean of the Coulter DxH 800/600 is 1.5397 with a standard deviation of 0.2376.  It is 95% confident that the sample mean falls between 1.467 and 1.612 or ±4.7%.

The difference between the two methods are within allowable error for 41 of 41 samples tested.


I did a method to method on EP evaluator.  Does this sound correct to you?

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