Now THAT is an excellent point, John! I assumed that the transfusion was being ordered for symptomatic relief with a Hgb at around 8. But if the clinician is just chasing a number on a patient, then the transfusion was unwarranted, regardless of the Hgb. I found two references on normal Hgb variation in healthy adult males of 0.6 (bed, ambulatory). Throw in 75 years old, ASHD, COPD, diabetes, and who knows what else, and the 2 gm change does not seem that far out of the realm of possibilities. But I would throw in clinical symptoms to the transfusion trigger.