Hi Esther, My own thoughts are that one would only use maternal blood for transfusion of a baby in extremis, when no other suitable blood is available. The danger of GvHD is a very real and present danger that can only be mitigated by irradiation of that blood. If your antibodies are anti-Cw, anti-K and anti-Lea, the chances are that the problem antibody of the three is the anti-K, but Cw-, K-, Le(a-) blood from unrelated donors would be readily available, and I would choose this blood ahead of maternal blood every time. Whilst your own red cells would be compatible (assuming that you are the same, or have a compatible ABO blood group as your baby, which is not necessarily the case) your blood would also have to be washed free of the "offending" antibodies in the plasma, prior to irradiation, and the more manipulation of the unit, however careful one can be, the more chance that there is of bacterial contamination. The answers to your two questions, in my opinion are, therefore: 1. It is important to avoid giving your baby maternal blood, unless there is no alternative, and 2. I think that you would be wise to accept the advice of the Blood Bank that is not interested.