Malcolm Needs

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My pleasure.

Vis-a vis Sc:-3 blood, I remember when I was working as a VERY junior member of staff in the IBGRL Red Cell Reference Laboratory of Dr Carolyn Giles and Joyce Poole, we did a family study following the relatives of an Sc:-3 female in a small village in Papua New Guinea (PNG), and we found six others. This was at least 40 years ago now, but it may be worthwhile contacting the PNG Blood Service to see if any of them are still donors, or, indeed, if they have found any other such donors.

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I just answered this question. My Score FAIL That's embarrassing!!!!!!!!!!!!!!!!!!!!!

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I'm sorry, but I just don't believe the member who says they are 122 (Oh, I dunno though - I've just looked in the mirror!!!!!!!!!!!!!!!!!!!!).

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Most certainly, you need to have a thorough transfusion history on the patient, as my good friend Yanxia says above, but it also depends upon the condition of the patient. If the patient is exsanguinating, the old adage comes into play that it is not a medical triumph to give perfectly compatible blood to a corpse, when, in very many cases these days, a haemolytic transfusion reaction can be treated. HOWEVER, it is ALWAYS a decision to be made by a medically qualified person, rather than a laboratory qualified person to make, as to how urgent the transfusion may be. IF there is time, it is always worthwhile doing a few more investigations. For example, is the patient DAT Positive, and, if so, is it IgG, IgM, IgA (rare), complement or a combination? Is the reaction seen in the auto-control due to a "cold" auto-antibody, or something else. To repeat what I wrote above, it MUST always be a decision for a medically qualified person, rather than a "lab rat" (HATE that term, but I hope you know what I mean, without taking offence - being a retired "lab rat" myself), but, if it was a case with which I was dealing, apart from doing a few basic tests (see above) I would be happy to give the blood - and more importantly, receive the blood, if I were the patient.

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I agree entirely, EXCEPT, we should think of females of child bearing POTENTIAL, rather than child bearing AGE. Think, for a moment, of a female who is group A, D Negative, who is, for example, 11 years old. Sorry to be picky, but, so often, these female children do not get the anti-D immunoglobulin they should be given.

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