diplomatic_scarf

"Sure it could happen ,,, and here's how... one of the parents perhaps has the Bombay phenotype"

I disagree. Most gel cards and Anti-D reagents won't detect DVI for patients. Fortunately I can find numerous suitable quotes, because it's true. https://labs-inc.org/pdf/361_3.pdf

Yes, I know. I was talking about patients on my original post.

"Modern anti-D reagents, while they are very good at detecting weaker forms of the D antigen, are specifically designed to NOT detect the most common form of partial D in Caucasians (DVI, or “D six”), so most Caucasian partial D patients will test as D-negative." -BloodBank Guy https://www.bbguy.org/education/glossary/glp04/

I think most modern Anti-D reagents won't detect DVI and these patients will test as D-negative. This is probably the answer. Anyways, this is the answer he gave his students. To me, the answer looks as vague as the question. Not "straight forward" at all. IMG_2756.heic

Yes, I don't think the original question setter meant the question to be a difficult one to answer. He is teaching a beginner level MLT course. He said there was only one correct "straight forward" answer. Just my opinion , but I think this person has no business teaching college level blood banking. As far as I know, he is a MLT with no experience with the tube, slide, or microplate testing methods, so I highly doubt he was talking about Anti-D reagents being the source of the discrepancy. But I could be wrong. I apologize for wasting people's time with this. I just can't understand how

No DAT. There are no other details to the question. Also DATs are not required testing for blood donations. I’m just trying to get people’s opinion on the question. Personally I think it is a poorly written question and the person who wrote it has no clue what he’s talking about, but I’m here to get people’s thoughts on it. Thank you

"A donor unit obtained from a central blood bank was labeled as Group O, D-negative. When the hospital transfusion service confirmed the donor's type, the result was group O, D-positive. Investigation of the label issued at the blood bank verified the unit's correct labeling. How can you explain the discrepancy in the D type of this donor unit?" The person who wrote this question said it is a "critical thinking" question and there is only one correct answer.

I think this question is suited more for sysmex IT tech support. I don't know about these days with modern day techs, but in my experience, it's the techs that perform the cell counts using a miller disc for the KB method. If your facility uses 300 uL dose RhIg, you can use this simple equation: (%fetal cells x 50) / 30 = number of vials of RhIg required. Remember to use the "fudge factor". Example: 1.3% fetal cells calculated on Kleihauer Betke stain 1.3 X 50 = 65 ml of fetal blood 65 ml/30 = 2.2 vials of RhIG required When the number to the right of

I have never heard of your references. The main texts for my course includes AABB technical manual by Fung, Harmening's Modern blood banking and transfusion services, and AABB's Standards for blood banking. I am only a part time SBB student, I work full time as a Medical Technologist. This is my final semester. You don't need to show me references I never heard of, I am certain you are right. Mom's with PARTIAL D (NOT WEAK D, WE DON'T TEST WEAK D FOR MOMS) can be typed as Rh positive, but still may form Anti-D when exposed to Rh positive red cells from baby(Modern Blood banking and transfusi

We do not do Weak D testing on mothers here where I work. This is a common practice in America

We don't do Weak D testing on adults, unless if they are donating blood.

I never said mother with weak D. Come on Malcolm, you know I didn't say mothers with weak D.

You know why Malcolm. If mom is Rh negative and baby is Rh positive, mom has 16% chance of developing anti-D after her first pregnancy. Moms with partial D can be classified as Rh Positive, but may still require RhIg to prevent HDFN. Our policy is to do weak D testing on all newborns who test D negative when we do the ABO/Rh forward typing.

We do weak D testing on all cords bloods that test negative with Anti-D. Regardless if the mom is Rh positive or negative.