We transfuse Rh pos platelets to Rh neg patients often, however, our policy is to call the nursing unit (or doctor) and let them know when their patient needs Rh(D) Immune Globulin. We check on a daily basis and call when any Rh neg male or female, up to 50 years of age, requires Rh(D)IG after receiving pos platelets. We base this on: 300 microgram Rh(D)IG will suffice for either 30 units of single donor platelets (counting each platelet apheresis as 4 single donor units) OR up to one month from the last dose of Rh(D)IG. Gail