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Everything posted by Abid
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Although this is an old case however I believe all threads should last forever. I agree with Lekota’s boss in that the patient has auto antibody and anti-K. Maybe the boss did not explain her conclusion. I would say, some auto antibodies are so weak and would not be detected unless enchantments media is used. However when you do the usual autocontrol by gel you always incubate cells with serum in LISS. LISS enhances antibody attachment to antigen. Where in circulation there is no enhancement media only time works. I suggest two things to make sure a combination of positive autocontrol and negative DAT is a real autoantibody: 1. Do the autocontrol without enhancement media (tube technique). The auto control will be negative. 2. Re-do the panel with the elute from autoadsorption, all cells which became negative will be Positive again. This only my thoughts.
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If it is unavoidable to transfuse Rh+ plt to Rh neg, RhIG should be considered in adult patients.(AABB) However for infents the doctor should makes the decision !?
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Hi I know we do not need to repeat antibody screen to infants less than 4 months old because they would not devolop new antibody. So can we give D pos pletelat, FFP or RBC to D neg Infants? Regards Abid
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Icteric serum appear after 3 to 6 h of hemolytic transfusion reaction. Before this time the serum would be reddish or pink. Was the original serum used for x-match icteric? The drop of Hb may be due to ongoing bleeding. Maybe the reaction was not hemolytic!
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JohnT who is Malcolm and what do you mean by TATs? Are you talking to me?
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If the patient BG look like O pos or Neg and the Ab screen pos in all phases, I would think that the patient has antibody to high prevalence such as Anti-H in bumpy blood group or Anti-HI, Anti-I, Anti-Vel, Anti-Tja etc….