Hello Everyone, What is everyone doing once they have found a positive IS crossmatch, but the gel crossmatch is negative. I can go ahead and prove there is a "cold antibody", but that does not prove ABO compatibility. We already re-type our donor units, and preform two ABO/Rh on two separate patient specimens. Can we give type specific units, or do we have to transfuse group O. Seems to me, if we must perform IS crossmatch to verify ABO compatibility then if the IS crossmatch is incomplatible we should be transfusing group O. Thoughts? Help!