Complement Query - do you know your C3bBbP from your C3bBbPC3b?

[AndyMiller]

Hi All

I'm having problems with complement and need the advice of a proper haematologists (rather than a transfusion bod like myself.

Does anybody know HOW C3bBbP gets converted into C3bBbPC3b (the C5 convertase)? The magenta bit on the right of the attached diagram

I don't have a problem that it does happen but I can't seem to track down anywhere how it actually happens.

Any help would be very much appreciated because it is starting to drive me mead now

Andy

[Malcolm Needs ☆]

Hi All

Any help would be very much appreciated because it is starting to drive me mead now

Andy

Hi Andy.

I know how you feel, but try to keep off the mead; it's quite a strong drink you know!!!!!

:D:D:D:D